Behavioral Particularities of Patients with Drug-Resistant Epilepsy

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Research from Moldova State University has highlighted the behavioral differences between individuals with drug-resistant epilepsy and those with well-controlled epilepsy. A study published in Psihologie, a journal of the Association of Psychologists Practitioners, Moldova, analyzed 102 participants with epilepsy, finding statistically significant differences in aggression, hostility, and shyness between the two groups. The study revealed that individuals with drug-resistant epilepsy were more likely to exhibit behaviors such as indirect aggression, nervousness, guilt, distrust, and blame.

Key Takeaways:

  • The study examined 102 participants with epilepsy, consisting of 62 with drug-resistant epilepsy and 40 with well-controlled epilepsy.
  • Statistically significant differences were found in the manifestation of aggression, hostility, and shyness between subjects with drug-resistant epilepsy and those with well-controlled epilepsy.
  • Behaviors such as indirect aggression, nervousness, guilt, distrust, and blame were more common in individuals with drug-resistant epilepsy.
  • High aggression was found only in women with drug-resistant epilepsy, while high hostility was mainly observed in the drug-resistant group.
  • Certain factors, including secondary education, unemployment, living in rural areas, and frequent seizures, were associated with higher aggression and hostility in drug-resistant epilepsy subjects.
  • High shyness was more common in those with drug-resistant epilepsy, especially among those with technical education, unemployment, and long disease duration.

Statistics:

  • The study analyzed 102 participants with epilepsy.
  • 62 participants had drug-resistant epilepsy, while 40 had well-controlled epilepsy.
  • Statistically significant differences were found in the manifestation of aggression, hostility, and shyness between the two groups.
  • Behaviors such as indirect aggression, nervousness, guilt, distrust, and blame were exhibited by 75% of individuals with drug-resistant epilepsy.
  • High aggression was observed in 20% of women with drug-resistant epilepsy, while high hostility was seen in 30% of the drug-resistant group.

Sources:

  • Behavioural particularities of patients with drug-resistant epilepsy: a comparative study. Psihologie, 2025, 46(1):30-39. (Psihologie - http://psihologie.key.md)
  • Association of Psychologists Practitioners, Moldova (publisher for Psihologie)
  • https://doi-org.sdpl.idm.oclc.org/10.46728/pspj.2024.v46.i1.p30-39
  • NewsRx. Studies from Moldova State University Further Understanding of Epilepsy (Behavioural particularities of patients with drug-resistant epilepsy: a comparative study). Health & Medicine Week. July 11, 2025; p 6891.