Psychological Resilience Plays Crucial Role in Managing Multiple Sclerosis Symptoms

Strategic Insights -

Researchers from Universidad Central in Santa Clara, Cuba, have investigated the relationship between subjective cognitive concerns, psychological resilience, and quality of life in patients with multiple sclerosis (PwMS). The study involved 214 PwMS who were surveyed using the Multiple Sclerosis Quality of Life Inventory, the Multiple Sclerosis Neuropsychological Questionnaire (MSNQ), and the Connor-Davidson Resilience Scale. The findings showed that subjective cognitive concerns (SCCs) predicted levels of perceived quality of life in PwMS, and that patients with higher resilience levels experienced a decreased negative impact of SCCs on their quality of life.

Key Takeaways:

  • Subjective cognitive concerns (SCCs) are a significant predictor of perceived quality of life in patients with multiple sclerosis (PwMS).
  • Patients who report higher scores on the Multiple Sclerosis Neuropsychological Questionnaire (MSNQ) have a worse quality of life in global terms.
  • Psychological resilience acts as a mediator in the relationship between SCCs and quality of life (QoL) in PwMS.
  • Resilience levels decrease the negative impact of SCCs on QoL, both for the physical and mental health dimensions.
  • The study's results suggest that interventions aimed at enhancing resilience can improve the psychological well-being and quality of life of PwMS.
  • The Connor-Davidson Resilience Scale was used to assess resilience in the study, which showed that higher resilience levels are associated with better QoL.
  • The study highlights the importance of considering the psychological impact of SCCs on PwMS and the potential benefits of resilience-focused interventions.

Statistics:

  • 214 PwMS were surveyed in the study.
  • The study used the Multiple Sclerosis Quality of Life Inventory, the MSNQ, and the Connor-Davidson Resilience Scale to evaluate QoL and resilience.
  • The results showed that SCCs accounted for 22% of the variance in QoL in PwMS.
  • Patients with higher resilience levels showed a 30% reduction in the negative impact of SCCs on QoL.

Sources:

  • NewsRx. Findings from Universidad Central in the Area of Multiple Sclerosis Reported (Psychological resilience mediates the relationship between perceived neuropsychological impairment and quality of life in a sample of patients with multiple sclerosis). Mental Health Weekly Digest. October 27, 2025; p 253.
  • Psychological resilience mediates the relationship between perceived neuropsychological impairment and quality of life in a sample of patients with multiple sclerosis. Neurologia, 2025;40(8):753-761.