Multidrug Resistant Tuberculosis Remains Public Health Threat in China

Researchers from Ningbo University of Finance and Economics have published a new report on the ongoing public health threat posed by multidrug-resistant tuberculosis (MDR-TB) in China. The study, which analyzed data from patients enrolled between 2015 and 2021, identified several risk factors associated with hospital readmission for MDR-TB patients. The findings highlight the need for continued investment in social health protection schemes and government financing to ensure early diagnosis and treatment of the disease.

Key Takeaways:

  • The study included 337 patients with a total of 1,255 hospitalization records analyzed, with a median follow-up period of 46 months.
  • Younger age (HR = 0.34, 95% CI: 0.20-0.57) and residing in urban areas (HR = 0.55, 95% CI: 0.37-0.83) were identified as protective factors against hospital readmission for MDR-TB patients.
  • Outdoor service workers (HR = 1.51, 95% CI: 1.01-2.26) and migrants (HR = 1.79, 95% CI: 1.07-2.98) were associated with an increased risk of hospital readmissions for MDR-TB patients.
  • The extended Cox model revealed that both migrant status and the use of Group B medications significantly elevated the risk of hospital readmission for MDR-TB patients.
  • The study found that MDR-TB patients in rural areas and migrants had an increased risk of hospital readmission.
  • Social health protection schemes and government financing are essential for ensuring early diagnosis and appropriate treatment of MDR-TB.

Statistics:

  • The study included 337 patients with a total of 1,255 hospitalization records analyzed.
  • The median follow-up period was 46 months.
  • Younger age was associated with a 66% reduced risk of hospital readmission (HR = 0.34, 95% CI: 0.20-0.57).
  • Residing in urban areas was associated with a 45% reduced risk of hospital readmission (HR = 0.55, 95% CI: 0.37-0.83).
  • Outdoor service workers had a 51% increased risk of hospital readmission (HR = 1.51, 95% CI: 1.01-2.26).
  • Migrants had a 79% increased risk of hospital readmission (HR = 1.79, 95% CI: 1.07-2.98).
  • Migrant status and the use of Group B medications significantly elevated the risk of hospital readmission for MDR-TB patients.

Sources:

  • Huang, J., Sang, G., Bi, J., Che, Y., & Lin, Y. (2025). Risk factors for hospital readmission of multidrug-resistant tuberculosis: evidence of longitudinal follow-up data in Ningbo, China. Frontiers in Public Health, 13. doi: 10.3389/fpubh.2025.1657931