Advances in Nanotechnology: QCM-Based Ammonia Gas Sensors for Liver and Kidney Disease Detection

Researchers from Universitas Negeri Yogyakarta have published a review on the development of ammonia gas sensors using quartz crystal microbalance (QCM)-based platforms with electrospun polymer-based nanofibers. The study highlights the potential of these sensors in directly detecting ammonia as a biomarker for liver and kidney diseases. The researchers discuss the key performance parameters of QCM-based ammonia gas sensors, including sensitivity, detection range, detection limit, and response/recovery time.

Key Takeaways:

  • The review focuses on recent research on ammonia gas sensors based on QCM with an electrospun polymer-based nanofiber active layer.
  • The discussion starts with the principle of QCM as a base sensor and then follows with the effect of electrospinning parameters on the fabricated nanofiber.
  • The potential of fabricated QCM-based sensors in directly detecting ammonia as a biomarker of liver and kidney diseases is comprehensively discussed.
  • The key performance parameters of QCM-based ammonia gas sensors, such as sensitivity, detection range, detection limit, and response/recovery time, are discussed in detail.
  • The researchers consider the potential, current challenges, and future perspectives on the application of QCM-based ammonia gas sensors for direct detection of liver and kidney diseases.
  • Improving selectivity, humidity resistance, and clinical translation are considered as potential areas for future research.

Statistics:

  • The study focuses on the development of QCM-based ammonia gas sensors with electrospun polymer-based nanofibers.
  • The key performance parameters of QCM-based ammonia gas sensors, including sensitivity, detection range, detection limit, and response/recovery time, are comprehensively discussed.
  • The researchers consider the potential, current challenges, and future perspectives on the application of QCM-based ammonia gas sensors for direct detection of liver and kidney diseases.

Sources:

  • QCM-based ammonia gas sensors with electrospun polymer-based nanofibers for liver and kidney disease detection: a mini-review. Journal of Materials Chemistry B, 2025.
  • Royal Soc Chemistry, Thomas Graham House, Science Park, Milton Rd, Cambridge CB4 0WF, Cambs, England.
  • Egadwinanda Nabila Suhandhia Putri, Dept. of Natural Science Education, Faculty of Mathematics and Natural Sciences, Universitas Negeri Yogyakarta, Jl. Colombo No. 1, Karangmalang, Yogyakarta 55281, Indonesia.
  • Rizky Aflaha, Chlara Naren Maharani, Laila Katriani, Ahmad Hasan As'ari, Aditya Rianjanu, Witha Berlian Kesuma Putri, Kuwat Triyana, Ruchi Gupta and Roto Roto.