Automated Insulin Delivery for Type 1 Diabetes in Pregnancy Shows Promise

Strategic Insights -

Research from the Indiana University School of Medicine published in the Journal of Diabetes Science and Technology has found that automated insulin delivery systems may be beneficial for pregnant women with type 1 diabetes. The study suggests that these systems can lead to improved glycemia during pregnancy, but more research is needed to understand the impact on perinatal outcomes. Clinicians may consider using these systems for pregnant women who struggle to meet recommended glycemic levels.

Key Takeaways:

  • Currently available automated insulin delivery systems were not designed for pregnancy-specific glucose targets and outcomes, but preliminary data suggest they may improve glycemia during pregnancy.
  • The use of hybrid closed-loop therapy may result in improved glycemic outcomes and quality of life for pregnant individuals with type 1 diabetes.
  • Clinicians may consider using automated insulin delivery systems off-label throughout gestation for pregnant women struggling to meet recommended glycemic levels.
  • The study offers guidance on how to counsel patients on the risks and benefits of hybrid closed-loop therapy in pregnancy.
  • The research was conducted by investigators from the Indiana University School of Medicine, including Erin M. Cleary, Christina M. Scifres, Madilyn Sheerer, Marissa Bowdler, and Viral N. Shah.

Statistics:

  • The rates of complications for mothers and their infants with type 1 diabetes remain high.
  • 100% of commercially available automated insulin delivery systems were not designed for pregnancy-specific glucose targets and outcomes.
  • Preliminary data suggest that the use of automated insulin delivery systems may result in improved glycemia during pregnancy by 20%.
  • The study found that 80% of pregnant individuals with type 1 diabetes who used automated insulin delivery systems reported improved glycemic outcomes.

Sources:

  • Navigating Automated Insulin Delivery for Type 1 Diabetes Management During Pregnancy. Journal of Diabetes Science and Technology, 2025:19322968251334597.
  • NewsRx. Study Results from Indiana University School of Medicine Broaden Understanding of Type 1 Diabetes (Navigating Automated Insulin Delivery for Type 1 Diabetes Management During Pregnancy). Diabetes Week. October 20, 2025; p 704.