Blood-Based Colorectal Cancer Screening Follow-Up Rates Fall Short

Strategic Insights -

Colorectal cancer is a leading cause of cancer-related deaths in the US, and regular screening can significantly improve survival rates. However, many individuals do not undergo screening due to various barriers, including fear, limited access, or challenges with test preparation. Blood-based screening tests offer a non-invasive and more convenient alternative to traditional tests, but their effectiveness depends on timely follow-up colonoscopies after abnormal results. A study by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that only 49% of patients completed a follow-up colonoscopy within six months, and 56% did so at any point during the two-year study period.

Key Takeaways:

  • Only 49% of patients completed a follow-up colonoscopy within six months after an abnormal blood-based colorectal cancer screening result.
  • The follow-up completion rate was 56% at any point during the two-year study period.
  • Individuals with Medicare Advantage were significantly less likely to complete follow-up colonoscopy compared to those with private insurance.
  • Patients with fewer health conditions were more likely to complete timely follow-up colonoscopy.
  • Unlike prior studies, race and ethnicity were not significant predictors of follow-up completion in this cohort.

Statistics:

  • 49% of patients completed a follow-up colonoscopy within six months after an abnormal blood-based colorectal cancer screening result.
  • 56% of patients completed a follow-up colonoscopy at any point during the two-year study period.
  • 6,000 individuals aged 45 and older received a blood-based colorectal cancer screening test between 2022 and 2024.
  • 452 individuals received an abnormal result and were included in the study.
  • 22% of patients with Medicare Advantage completed follow-up colonoscopy within six months, compared to 63% of patients with private insurance.

Sources:

  • Heady, D. (2023, January 1). Study Finds Blood-Based Colorectal Cancer Screening Follow-Up Rates Fall Short. UCLA Health System.
  • The study was published in the journal Gastroenterology.
  • UCLA Health System.
  • Shield (Guardant Health).