Consensus Recommendations for Liquid Nitrogen Spray Cryotherapy in Barrett's Esophagus and Esophageal Cancer

Strategic Insights -

Research has led to the development of consensus recommendations for the safe and appropriate use of liquid nitrogen spray cryotherapy in Barrett's esophagus and esophageal cancer. The study's goal was to create evidence-based guidelines for the use of this cryotherapy in these conditions. The research involved a modified Delphi process, where 19 experts assessed the strength of evidence for each recommendation. The process resulted in 41 out of 42 statements being accepted, either in their original version or after modification based on expert input.

Key Takeaways:

  • The study aimed to develop consensus recommendations for the safe and appropriate use of liquid nitrogen spray cryotherapy in Barrett's esophagus and esophageal cancer.
  • The research involved a modified Delphi process, where 19 experts assessed the strength of evidence for each recommendation.
  • 41 out of 42 statements were accepted, either in their original version or after modification based on expert input.
  • The recommendations were developed to guide safe and appropriate use of liquid nitrogen spray cryotherapy in Barrett's esophagus and esophageal cancer.
  • The research concluded that the developed recommendations can be used to guide safe and appropriate use of the therapy in these conditions.
  • The study's findings were published in the American Journal of Gastroenterology in 2025.
  • The recommendations were developed by a team of experts, including researchers from the Digestive Disease Institute and other institutions.

Statistics:

  • 19 experts participated in the modified Delphi process.
  • 41 out of 42 statements were accepted, either in their original version or after modification based on expert input.
  • The study involved 3 rounds of the modified Delphi process.
  • The research was published in the American Journal of Gastroenterology in 2025.

Sources:

  • NewsRx. Findings from Digestive Disease Institute in Barrett Esophagus Reported (Spray Cryotherapy Esophageal Consortium Consensus Recommendations for Liquid Nitrogen Spray Cryotherapy in Barrett's Esophagus and Esophageal Cancer Using a Modified ...). Cancer Weekly. October 21, 2025; p 512.
  • Spray Cryotherapy Esophageal Consortium Consensus Recommendations for Liquid Nitrogen Spray Cryotherapy in Barrett's Esophagus and Esophageal Cancer Using a Modified Delphi Process. American Journal of Gastroenterology, 2025.