Gastric Cancer Research Highlights Importance of Personalized Medicine in Early Detection and Diagnosis

Strategic Insights -

Gastric cancer remains a significant global health challenge, with researchers emphasizing the need for early detection and accurate prognosis for effective management. Investigators have conducted a bibliometric analysis of tumor marker application in gastric cancer diagnosis from 2019 to 2024, analyzing 2,940 articles from Scopus and Web of Science databases. The study highlights East Asia, particularly institutions like Fudan University and Nanjing Medical University, as a hub for groundbreaking research.

Key Takeaways:

  • The study analyzed 2,940 articles on tumor markers for gastric cancer diagnosis from 2019 to 2024, highlighting East Asia as a hub for research in this field.
  • Fudan University and Nanjing Medical University were identified as prominent institutions contributing to groundbreaking research in gastric cancer biomarkers.
  • The study emphasized the importance of personalized medicine and early detection strategies in improving outcomes for gastric cancer patients.
  • Visualization of global collaborations revealed extensive networks driving innovation in gastric cancer research.
  • The study identified limitations in current research, including language bias and a narrow temporal scope, highlighting the need for future research to prioritize novel biomarkers and integrate advanced technologies like AI.
  • The research concluded that future research should also aim to enhance international cooperation to further improve outcomes for gastric cancer patients.
  • Notable authors contributing to this research include Zhanat Komekbay, Reza Shirazi, Gulnaz Yessultanova, Alisher Garifollin, Anar Tulyayeva, Nurgul Kereyeva, Saule Akhmetova, and Abdiraman Kaliev.

Statistics:

  • 2,940 articles were analyzed in the bibliometric study on tumor markers for gastric cancer diagnosis from 2019 to 2024.
  • 78% of the articles were published in the Asia-Pacific region, with 40% occurring in China alone.
  • The top 5 publishing institutions contributing to research in gastric cancer biomarkers were Fudan University (14%), Nanjing Medical University (11%), West Kazakhstan Marat Ospanov Medical University (8%), Shanghai Jiao Tong University (7%), and Harbin Medical University (6%).
  • The study identified 12 key tumor markers for gastric cancer diagnosis, with the most frequently studied markers being CA 19-9, CA 125, and CEA.
  • The research highlighted that future research should prioritize novel biomarkers and aim to integrate advanced technologies like AI to enhance outcomes for gastric cancer patients.

Sources:

  • "Bibliometric analysis of tumor marker application in gastric cancer diagnosis from 2019 to 2024" (Frontiers in Medicine, 2025, 12)
  • NewsRx (Health & Medicine Week, May 23, 2025; p 5399)