Genetic Diversity of HSP70 Gene in Bali Cattle Analyzed

Researchers at IPB University have published a new study on the genetic diversity of the Heat Shock Protein 70 (HSP70) gene in Bali cattle. The study aimed to investigate the genetic diversity of the HSP70 gene in the coding sequence (CDS) region and its association with physiological responses in Bali cattle. The researchers analyzed 62 Bali cattle from two different locations in Bali and found nine SNPs within the CDS region of the HSP70 gene.

Key Takeaways:

  • The study aimed to investigate the genetic diversity of the HSP70 gene in the coding sequence (CDS) region and its association with physiological responses in Bali cattle.
  • The researchers analyzed 62 Bali cattle from two different locations in Bali and found nine SNPs within the CDS region of the HSP70 gene, comprising eight synonymous SNPs and one nonsynonymous SNP.
  • The SNP diversity in the coding sequence of the HSP70 gene showed no significant association with physiological responses, including respiratory rate, heart rate, rectal temperature, and heat tolerance coefficient (HTC).
  • The SNPs discovered in the coding region of the HSP70 gene exhibited polymorphism in Bali cattle.
  • The study considered the Bali cattle samples used in the research as consisting of 62 Bali cattle from two different locations in Bali and Se-rading.
  • The diversity of SNPs in the coding sequence of the HSP70 gene was determined using the FinchTV 1.4.0 application and version X of the Molecular Evolutionary Genetic Analysis (MEGA) program.
  • The association of HSP70 gene SNPs with physiological responses in Bali cattle was evaluated using the GLM method in IBM SPSS Statistics 26.

Statistics:

  • 62 Bali cattle samples were analyzed in the study.
  • 9 SNPs were discovered within the CDS region of the HSP70 gene, comprising 8 synonymous SNPs and 1 nonsynonymous SNP.
  • The study found no significant association (P < 0.05) between SNP diversity in the coding sequence of the HSP70 gene and physiological responses.

Sources:

  • "Genetic diversity of coding sequence (CDS) region of HSP70 gene in Bali cattle." Journal of the Indonesian Tropical Animal Agriculture, 2025, 50(2):103-110. (Journal of the Indonesian Tropical Animal Agriculture - http://ejournal.undip.ac.id/index.php/jitaa)
  • Y. G. M. Bonawati, Postgraduate student of Animal Production and Technology, IPB University, Indonesia
  • I. Suhendro, J. Jakaria, R. R. Noor, researchers from IPB University.