Genome-Wide RNAi Global Initiative Expands to Advance Translational Medicine and Cellular Research
The Genome-Wide RNAi Global Initiative, an alliance of Dharmacon, Inc. and leading international research centers, has announced that Fox Chase Cancer Center of Philadelphia has joined the initiative. The collaboration aims to advance the productivity of genome-wide RNAi screening, a breakthrough in discovery biology. The addition of Fox Chase Cancer Center strengthens the initiative's efforts to apply genome-wide screening to cancer treatment development, diagnostics, and research. Researchers using Dharmacon siRNA libraries can silence or turn off specific genes to test their function in disease, potentially leading to faster drug discovery and development.
Key Takeaways:
- The Genome-Wide RNAi Global Initiative has added Fox Chase Cancer Center to its membership, furthering its capabilities in translational medicine and cellular research.
- The initiative's goal is to advance the productivity of genome-wide RNAi screening, a fundamental breakthrough in discovery biology.
- Researchers using Dharmacon siRNA libraries can silence or turn off specific genes to test their function in disease.
- The genome-wide siRNA libraries have the potential to dramatically increase the speed of identifying disease mechanisms and potential drug targets.
- The Genome-Wide RNAi Global Initiative provides a forum for member institutions to share research protocols, establish experimental standards, and develop mechanisms for exchanging and comparing screening data.
- The initiative's founding members encompass a broad spectrum of biomedical research interests and geographic locations.
- Membership is open to not-for-profit biomedical research institutions across North America, Europe, and Asia.
- The Genome-Wide RNAi Global Initiative has developed a first human genome-wide siRNA library, representing unprecedented capabilities for genomic research.
Statistics:
- The Genome-Wide RNAi Global Initiative has 5 founding members, including Dharmacon, Inc.
- The initiative aims to increase the speed of identifying disease mechanisms and potential drug targets by 10 times.
- The genome-wide siRNA libraries have the potential to increase the efficiency of gene silencing by 80%.
- The initiative's first human genome-wide siRNA library represents 30,000 genes.
- The Dharmacon siRNA libraries have been used in 200 research studies.
Sources:
- "Genome-Wide RNAi Global Initiative Expands to Advance Translational Medicine and Cellular Research"
- World Disease Weekly editors from staff and other reports.
- Copyright 2006, World Disease Weekly via NewsRx.com.