Global Research Trends in BPaL and BPaLM Regimens for Drug-Resistant Tuberculosis: A Bibliometric Analysis

Strategic Insights -

Researchers from the Arabian Gulf University have published a study on the global research trends in BPaL and BPaLM regimens for drug-resistant tuberculosis, revealing the introduction of these regimens has revolutionized treatment, offering superior efficacy and tolerability. The study analyzed Scopus-indexed publications, identifying 1,081 authors and 120 studies meeting inclusion criteria, with publications growing at 11.61% annually and peaking in 2024. International collaborations were featured in 53.33% of studies, led by the US, UK, and South Africa.

Key Takeaways:

  • The introduction of BPaL and BPaLM regimens for drug-resistant tuberculosis has improved treatment efficacy and tolerability.
  • The study analyzed 120 Scopus-indexed publications, identifying 1,081 authors and publications growing at 11.61% annually.
  • International collaborations were featured in 53.33% of studies, with the US, UK, and South Africa leading the way.
  • Johns Hopkins University was the top institution, and Antimicrobial Agents and Chemotherapy was the leading journal.
  • Landmark 2019 publications had the highest citation rate (13.05/year).
  • Thematic analysis revealed three domains: pathogen and drug resistance, treatment regimens and efficacy, and demographics and clinical studies.
  • Strong collaborations linked high-income and high-burden countries, notably the US and South Africa.
  • The study highlights progress in evidence generation but reveals gaps in implementation science and equitable knowledge production.

Statistics:

  • 1,081 authors were identified in the study.
  • 120 studies met inclusion criteria.
  • Publications grew at 11.61% annually.
  • 53.33% of studies featured international collaborations.
  • The US led with 56 studies, followed by the UK (25) and South Africa (20).
  • Johns Hopkins University was the top institution (n = 56).
  • Antimicrobial Agents and Chemotherapy was the leading journal (n = 15).
  • Landmark 2019 publications had a citation rate of 13.05/year.

Sources:

  • Global research trends in BPaL and BPaLM regimens for drug-resistant tuberculosis: a bibliometric analysis. Tropical Diseases, Travel Medicine and Vaccines, 2025, 11(1):1-10.
  • Tropical Diseases, Travel Medicine and Vaccines - http://www.tdtmvjournal.com/
  • Publisher: BMC