Green Synthesis of Copper Nanoparticles Using Momordica Cymbalaria Fruit

Strategic Insights -

Researchers have successfully developed a new method for synthesizing eco-friendly copper nanoparticles using the extract of Momordica cymbalaria fruit. These nanoparticles have shown promising antibacterial, antioxidant, and anti-inflammatory properties, making them suitable for biomedical applications. The study, conducted by scientists at Yogi Vemana University in Andhra Pradesh, India, demonstrates the potential of using plant-based materials to produce nanoparticles.

Key Takeaways:

  • The researchers synthesized copper nanoparticles with an average size of approximately 14 nm using the extract of Momordica cymbalaria fruit.
  • The nanoparticles exhibited significant antibacterial activity against Proteus vulgaris and Staphylococcus aureus, with zone of inhibition values of 23.1 ± 0.8 mm and 23.3 ± 2.0 mm, respectively.
  • The MC-CuNPs showed potential in scavenging free radicals and H2O2, with IC50 values of 100 and 50 mg/ml, respectively.
  • The anti-inflammatory properties of the nanoparticles were evaluated against egg albumin's protein denaturation, with the highest level of protein inhibition recorded at 500 mg/ml of MC-CuNPs.

Statistics:

  • Average size of copper nanoparticles: 14 nm
  • Zone of inhibition against Proteus vulgaris: 23.1 ± 0.8 mm
  • Zone of inhibition against Staphylococcus aureus: 23.3 ± 2.0 mm
  • IC50 value for total antioxidant activity: 100 mg/ml
  • IC50 value for H2O2 scavenging activity: 50 mg/ml

Sources:

  • Phytofabrication of copper nanoparticles using Momordica cymbalaria fruit extract and their antibacterial, antioxidant and anti-inflammatory properties. Hybrid Advances, 2025(9):100421
  • Yogi Vemana University, Kadapa, Andhra Pradesh, India, 516005
  • NewsRx. Study Findings on Nanoparticles Detailed by Researchers at Yogi Vemana University (Phytofabrication of copper nanoparticles using Momordica cymbalaria fruit extract and their antibacterial, antioxidant and anti-inflammatory properties). Nanotechnology Weekly. June 9, 2025; p 1870