Groundbreaking Study at University of Louisville Enables Children with Complete Spinal Cord Paralysis to Take Steps

Strategic Insights -

A revolutionary technique combining external electrical stimulation, activity-based therapy, and conscious intent has enabled five children with complete spinal cord paralysis to take steps. The study, led by Professor Andrea Behrman, director of the Center for Pediatric NeuroRecovery at the University of Louisville, used a noninvasive, transcutaneous electrical stimulation method developed by Yury Gerasimenko to stimulate the sensory nerves of the spinal cord. The children, ages 7-12, underwent 60 sessions of this therapy, which included activity-based locomotor training and encouragement to consciously attempt to step.

Key Takeaways:

  • The study shows that electrical stimulation can "charge" the spinal cord, making it possible for paralyzed individuals to step voluntarily.
  • The technique involves a combination of external electrical stimulation, activity-based therapy, and conscious intent to step.
  • The children in the study underwent 60 sessions of therapy, which included transcutaneous electrical stimulation and activity-based locomotor training.
  • All five children gained the ability to take steps and experienced improvements in sensation, bladder function, transferring, and other abilities.
  • The study found that the children's ability to step increased over time when the stimulation was combined with locomotor training and mental intent to step.
  • Three to six months after the sessions were completed, all of the children were still able to take steps with and without the stimulation.
  • The study shows that the spinal cord can process information, work like a battery, and help produce steps and respond to therapy.
  • The children in the study showed significant positive impact on their quality of life and health, with several retaining benefits three years after the study concluded.

Statistics:

  • 5 children with complete spinal cord paralysis participated in the study.
  • 60 sessions of therapy were completed by each child.
  • The therapy sessions included noninvasive electrical stimulation of the sensory nerves to the spinal cord.
  • 100% of the children gained the ability to take steps.
  • 100% of the children experienced improvements in sensation, bladder function, transferring, and other abilities.
  • 3-6 months after the sessions were completed, all children were still able to take steps with and without stimulation.

Sources:

  • "Children with spinal cord injuries 'walk' again thanks to University of Louisville study" (prnewswire.com, Oct. 30, 2025)
  • "Study says sparking spinal cord can help paralyzed walk again" (prnewswire.com, Oct. 30, 2025)
  • "Spinal Cord Stimulation for Spinal Cord Injuries - A New Era for Treatment" (nih.gov)
  • University of Louisville