Human Papillomavirus Vaccines Show Promise in Reducing Infection Rates in Weifang City, China

Strategic Insights -

A recent study published in the Journal of Medical Virology has shed light on the prevalence of human papillomavirus (HPV) infections in Weifang City, China. The research, conducted from 2012 to 2023, collected a total of 81,397 specimens of cervical epithelium and found that the overall infection rate of HPV was 23.78%, with the infection rate of high-risk HPV being 18.36%. The study suggests that HPV vaccination may influence the trend of HPV infection and provides an epidemiological basis for disease prevention in the region.

Key Takeaways:

  • The study collected a total of 81,397 specimens of cervical epithelium from 2012 to 2023 in Weifang City, China.
  • The overall infection rate of HPV was 23.78%, with the infection rate of high-risk HPV being 18.36%.
  • The top five most prevalent subtypes of HPV were HPV16, 52, 58, 51, and 68.
  • The infection rate of low-risk HPV was 5.42%, with the most common subtypes being HPV53, 81, and 66.
  • People aged 18-24 years and those aged 55 years exhibited higher infection rates, which were 33.55% and 26.29%, respectively.
  • The predominant type of infection was single infection, followed by double infection.
  • Joinpoint regression analysis revealed that the infection rates of HPV and HR-HPV exhibited a downward trend over time.

Statistics:

  • Overall infection rate of HPV: 23.78%
  • Infection rate of high-risk HPV: 18.36%
  • Top five most prevalent subtypes of HPV: HPV16 (6.44%), 52 (1.74%), 58 (1.64%), 51 (1.44%), and 68 (1.34%)
  • Infection rate of low-risk HPV: 5.42%
  • Most common subtypes of low-risk HPV: HPV53 (0.46%), 81 (0.35%), and 66 (0.29%)
  • Age groups with higher infection rates: 18-24 years (33.55%) and 55 years (26.29%)
  • Predominant type of infection: single infection (74.14%)
  • Double infection rate: 4.54%

Sources:

  • Trend Analysis of HPV Prevalence in Weifang City Using a Bayesian Structural Time Series Model: A Longitudinal Study From 2012 to 2023. Journal of Medical Virology, 2025;97(10).
  • Weifang Maternal and Child Health Hospital, Weifang, Shandong Province, People's Republic of China.
  • Jian Xu, Haoran Yang, Hongwei Wang, Hong Kou, Xiao Yang, and Jing Li.