Melatonin Concomitant Use with Neoadjuvant Chemotherapy Protocols in Breast Cancer Patients: An Ongoing Clinical Trial

Strategic Insights -

Mansoura University has initiated an interventional clinical trial to evaluate the efficacy of melatonin concomitant use with neoadjuvant chemotherapy protocols in breast cancer patients. The study aims to investigate the potential anticancer properties of melatonin, which has been reported to exhibit antioxidant, immunomodulating, oncostatic, antiproliferative, and estrogen-modulating properties. The trial involves a sample of 80 participants from the USA and is expected to provide valuable insights into the effects of melatonin on breast cancer treatment outcomes.

Key Takeaways:

  • The trial aims to investigate the potential anticancer effects of melatonin in breast cancer patients using a combination of neoadjuvant chemotherapy protocols.
  • Melatonin has been reported to exhibit antioxidant, immunomodulating, oncostatic, antiproliferative, and estrogen-modulating properties, which may contribute to its anticancer effects.
  • The study will evaluate the effect of melatonin on chemotherapy-induced toxicities in breast cancer patients.
  • Preclinical studies have demonstrated the antitumor effects of melatonin when used alone and enhanced effects for chemotherapy when used in combination.
  • The effect of melatonin in early stages and locally advanced breast cancer is still questioned, and this trial aims to provide more information on this topic.
  • The study will recruit 80 participants from the USA and aims to provide valuable insights into the effects of melatonin on breast cancer treatment outcomes.

Statistics:

  • The trial involves a sample of 80 participants from the USA.
  • Melatonin has been reported to exert antiangiogenic and direct apoptotic effects.
  • Preclinical studies have demonstrated the antitumor effects of melatonin when used alone and enhanced effects for chemotherapy when used in combination.
  • Melatonin has shown positive results in a number of clinical trials on patients with cancer.

Sources:

  • ClinicalTrials.gov
  • Mansoura University
  • Contify.com (Copyright 2017)