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Technical institutes

Machine Learning-Based Approach to Modeling Anisotropic Behavior of Elastoplastic Materials

Researchers from Northwestern Polytechnic University have developed a machine learning-based data-driven approach to model anisotropic and tension-compression asymmetry behavior of elastoplastic materials using limited experimental data. This innovative technique utilizes artificial neural networks to improve the predictive capability under unknown large deformations. The proposed approach has been successfully applied to

Diabetes therapy

GLP-1 Receptor Polymorphism Alters Efficacy of Liraglutide Treatment in Individuals with Obesity

Researchers at Vanderbilt University Medical Center have identified a genetic variant in the glucagon-like peptide-1 receptor (GLP-1R) that influences the effectiveness of liraglutide, a medication used to treat obesity and pre-diabetes. The study, published in the Journal of Endocrinology, found that individuals with the variant allele (rs6923761) experienced greater weight

COVID-19

Africa Urged to Integrate Health Security Reforms into Broad Health Systems Strengthening

Researchers at the World Health Organization (WHO) are advocating for African countries to prioritize health security reforms as part of broader health systems strengthening efforts. The proposed approach aims to improve key dimensions such as service delivery, governance, financing, surveillance, and workforce development, ultimately promoting health security and accelerating universal

Type 2 diabetes

Patent Application for Treating Metabolic Disorders with Antagonistic Binding Proteins for GIPR/GLP-1 Receptor Agonist Fusion Proteins

Researchers have developed a novel approach to treating metabolic disorders by fusing a GLP-1 receptor agonist polypeptide with an antagonist glucose-dependent insulinotropic polypeptide receptor (GIPR) antigen binding protein. This fusion protein has shown promise in reducing body weight, improving insulin sensitivity, and promoting glucose tolerance. According to the patent application,