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Amphotericin B

Long-Circulating Liposomes Show Promise in Treating Cutaneous Leishmaniasis

Researchers from the Federal University of Minas Gerais-UFMG have discovered a new therapeutic strategy for cutaneous leishmaniasis, a neglected tropical disease that affects socially vulnerable populations. Leishmaniasis is caused by various Leishmania species, and the current treatment, AmBisome, a commercial formulation of amphotericin B, has limitations in treating immunocompromised patients

Glycoproteins

Enhanced Diffusion and Retention of Proteoglycan Replacements in Cartilage Through Thermoresponsive Polyelectrolytes

Researchers at the University of Delaware have made a significant breakthrough in developing a new strategy for improving the delivery and retention of polyelectrolytes in solid tissue, specifically in cartilage explants. The study, published in Macromolecules, investigates the use of thermoresponsive block copolymers to enhance the diffusion and retention of