Rideshare Intervention Improves Colonoscopy Completion in Colorectal Cancer Screening

Strategic Insights -

Researchers have found that providing rideshare services to patients with abnormal fecal immunochemical test (FIT) results can significantly improve colonoscopy completion rates, leading to a reduction in colorectal cancer (CRC) cases and deaths. A microsimulation model was used to determine the outcomes and cost-effectiveness of a rideshare intervention in a population-based CRC screening program. The study found that increasing colonoscopy completion from 35% to 70% resulted in a reduction of CRC cases per 1000 by 26.3%, CRC deaths per 1000 by 32.5%, and 24.9 life-years gained per 1000.

Key Takeaways:

  • The study used the CRC-Simulated Population Model for Incidence and Natural History microsimulation model to simulate the outcomes and cost-effectiveness of a rideshare intervention in a population-based CRC screening program.
  • Four single-age cohorts (ages 45, 55, 65, and 70 years) of 10 million people each were simulated, with similar sex distribution as the US population.
  • Using a rideshare intervention starting at age 45 years that costs $100 per ride to increase colonoscopy completion from 35% to 70% was associated with a reduction in CRC cases per 1000 by 26.3% (30.7 vs 41.6 cases per 1000) and CRC deaths per 1000 by 32.5% (9.8 vs 14.6 cases per 1000).
  • The cost-effectiveness of the rideshare intervention was $43 308 per 1000 people screened and saved $330 587 per 1000 people screened.
  • The study concluded that a rideshare intervention to improve colonoscopy completion in a population with abnormal FIT results is cost saving up to $100 per ride.

Statistics:

  • Reduces CRC cases per 1000 by 26.3% (30.7 vs 41.6 cases per 1000)
  • Reduces CRC deaths per 1000 by 32.5% (9.8 vs 14.6 cases per 1000)
  • Increases life-years gained per 1000 by 24.9
  • Cost-effectiveness of the rideshare intervention is $43 308 per 1000 people screened and saves $330 587 per 1000 people screened
  • The rideshare intervention is cost saving up to $100 per ride

Sources:

  • Modeled Cost-Effectiveness of a Rideshare Program to Facilitate Colonoscopy Completion. JAMA Network Open, 2025;8(9).
  • Amer Medical Assoc, 330 N Wabash Ave, Ste 39300, Chicago, IL 60611-5885, USA.
  • Laura Matrajt, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  • Rachel B. Issaka, Pedro Nascimento de Lima, and Carolyn M. Rutter, authors of the study.