Standardized Medication Reconciliation Services Improve Clinical Outcomes in CHD Patients

Strategic Insights -

Researchers from Hebei North University published a study in the Pakistan Journal of Medical Sciences, reporting on the efficacy of pharmacist-conducted medication reconciliation services for chronic diseases in elderly patients with coronary atherosclerotic heart disease (CHD). The retrospective study involved 200 CHD patients who were randomly divided into a control group and an experimental group. The experimental group received standardized pharmacist-conducted medication reconciliation services in addition to conventional clinical treatment. The results showed that the experimental group had reduced prescription of potentially inappropriate medications (PIMs), length of hospital stay, drug costs, and incidence of adverse drug reactions (ADRs). The study concluded that standardized MR services for CHD patients may be conducive to ensuring rational medication and improving clinical effect.

Key Takeaways:

  • The study involved 200 CHD patients, randomly divided into a control group (n = 100) and an experimental group (n = 100).
  • The experimental group received standardized pharmacist-conducted medication reconciliation services in addition to conventional clinical treatment.
  • Compared to the control group, the experimental group exhibited reduced PIMs (not specified), length of hospital stay, drug costs, and incidence of ADRs.
  • The study had a 6-month follow-up period to assess patient satisfaction and medication adherence.
  • The study suggests that standardized MR services may improve clinical outcomes in CHD patients.

Statistics:

  • 200 CHD patients were involved in the study.
  • 100 patients were in the control group and 100 in the experimental group.
  • 6 months is the follow-up period for assessing patient satisfaction and medication adherence.
  • Reducing PIMs, length of hospital stay, drug costs, and incidence of ADRs are key benefits of standardized MR services.

Sources:

  • Pakistan Journal of Medical Sciences
  • "Efficacy of medication reconciliation in medication therapy for chronic diseases in elderly patients with coronary atherosclerotic heart disease." Pakistan Journal of Medical Sciences, 2025;41(9):2457-2462.
  • Naidong Wang, Naidong Wang Dept. of Pharmacy, Ji Nan Hospital, Jinan 250013, Shandong, People's Republic of China
  • Maodong Zheng, Xujun Hu, Juan Yan, and Yuhuan Cui (authors)
  • Professional Medical Publications, Panorama Centre, Rm 522, 5TH Floor, Bldg 2, Raja Ghazanfar Ali Rd, PO Box 8766, Saddar, Karachi 00000, Pakistan (publisher)
  • Cardiovascular Week, "New Chronic Disease Study Findings Reported from Naidong Wang and Co-Authors (Efficacy of medication reconciliation in medication therapy for chronic diseases in elderly patients with coronary atherosclerotic heart disease)" October 20, 2025; p 63.