Acute lymphocytic leukemia

Pediatrics

High-Dose Methotrexate Therapy in Pediatric Acute Lymphoblastic Leukemia: Research Highlights Faster Clearance and Reduced Hospital Stays

Researchers at Chang Gung University have conducted a study on the relationship between urine output and time to methotrexate clearance in pediatric leukemia patients receiving high-dose methotrexate therapy. The study found that patients with higher urine output showed significantly faster methotrexate clearance, lower incidence of delayed clearance, and shorter hospital