Diseases
Researchers at Peking University have made a significant discovery in the field of Alzheimer's disease research, revealing that the von Hippel-Lindau protein (VHL) plays a crucial role in restricting the progression of the disease. The study, published in the Journal of Molecular Cell Biology, demonstrates that VHL-mediated ubiquitination
Diseases
Alzheimer's disease (AD) research has continued to uncover the underlying mechanisms driving neurodegeneration. Investigators at the University of South Florida have published a groundbreaking study that sheds new light on the role of amyloid-beta (Ab) oligomers in disrupting synaptic function. The study, published in Cell Calcium, reveals that
Diseases
Researchers at Brigham and Women's Hospital have made a significant discovery in the field of immunology, developing two CNS-tau-specific monoclonal antibodies that can be used to diagnose and understand the progression of tau-related neurodegenerative diseases such as Alzheimer's disease. The antibodies, LL-T-1-1 and LL-T-1-5, were created
Enzymes
Researchers at the University of Jinan have made a groundbreaking discovery in the field of enzymes and coenzymes. According to their study, published in the journal ChemPhysMater, the combination of (-)-epigallocatechin-3-gallate (EGCG) and ferulic acid (FA) significantly enhances the activity of a-secretase (ADAM10), a protein involved in the pathogenesis
Alzheimer's disease
A recent study published in the Journal of Applied Gerontology has shed light on the relationship between cognitive activities, dementia risk, and residential settings in older adults. Researchers at Texas A&M University examined data from the Health and Retirement Study, spanning from 2012 to 2020, to assess the
Associations
Edward Jones, a financial services firm, has reaffirmed its commitment to promoting healthier futures for families and communities impacted by Alzheimer's and all other dementia through a renewed strategic alliance with the Alzheimer's Association. The firm's support will continue through 2030, with a $1
Air pollution
A recent study has made a significant breakthrough in predicting mild cognitive impairment (MCI) in middle-aged and elderly populations. Researchers from the Department of Chronic Disease, Chifeng Center for Disease Control and Prevention, in collaboration with international experts, have developed a novel MCI nomogram that integrates air pollution, sociodemographic, and
Alzheimer's disease
Research has been conducted on Alzheimer's disease, investigating the decline in cognitive functioning. The study focused on subjective cognitive decline (SCD), a condition considered at risk for mild cognitive impairment (MCI) and Alzheimer's disease (AD). The researchers used the Recency ratio (Rr), a measure of forgetting
Alzheimer's disease
Research at Anhui Medical University in Hefei, People's Republic of China, has explored sex differences in Alzheimer's disease (AD) progression, uncovering potential biomarkers and correlations with cognitive performance. The study, supported by the Scientific Research Project of University in Anhui Province, China, and the National Natural
Associations
The Alzheimer's Association has chosen Dr. Katerina Akassoglou, a senior investigator at Gladstone Institutes, as a recipient of the prestigious Zenith Fellows Award. Dr. Akassoglou's research has shed light on the interactions between the brain, blood vessels, and immune system, revealing how these interactions drive the
Alzheimer's disease
A new study published in the Journal of Physical Activity and Health has found that engaging in physical activity, such as walking or exercise, more than twice a week significantly reduces the risk of Alzheimer's disease and related dementias (AD/ADRD) in older adults with mild cognitive impairment.
Alzheimer's disease
Research conducted at the Karolinska Institute in Stockholm, Sweden, has found that statins, a type of cholesterol-lowering medication, may influence cognition in patients with Alzheimer's disease. The study, which analyzed data from the Swedish Registry for Dementia and Cognitive Disorders (SveDem) and Stockholm Creatinine Measurements (SCREAM) from 2007
