Associations
Edward Jones, a financial services firm, has reaffirmed its commitment to promoting healthier futures for families and communities impacted by Alzheimer's and all other dementia through a renewed strategic alliance with the Alzheimer's Association. The firm's support will continue through 2030, with a $1
Diseases
Alzheimer's disease is a chronic and progressive neurological condition that affects memory, thinking, and other cognitive functions, with approximately 60-80% of dementia cases attributed to it. The disease is strongly linked to the buildup of amyloid beta plaques and tau tangles in the brain, which interfere with neural
Medical research
A recent study published in the Health Affairs Scholar journal has shed light on the factors contributing to differences in total Medicare costs and drug spending among beneficiaries with and without Alzheimer's disease and related dementias (ADRD). Utilizing Medicare fee-for-service claims data from 2018, 2019, 2021, and 2022,
Medical research
Research has shed new light on the importance of small GTPases in regulating the phosphorylation, aggregation, and clearance of tau protein in Alzheimer's disease. According to a recent study published in the journal Frontiers in Cellular Neuroscience, small GTPases play a pivotal role in the dysregulation of tau
Medical research
Scientists have made a groundbreaking discovery in the brains of stranded dolphins, revealing striking similarities to Alzheimer's disease in humans. This finding, based on the examination of 22 marine mammals, emphasizes the potential impact of environmental factors, such as toxic algal blooms exacerbated by climate change and pollution,
Diseases
Rodney Scott, MBChB, MRCP, DipStat, PhD, Division Chief of Neurology at Nemours Children's Health, Delaware Valley, has been awarded a $2.6 million, five-year grant from the National Institutes of Health (NIH) to investigate malfunctions in the brain's hippocampal region. This research aims to identify patterns
Diseases
Scientists at Johns Hopkins Medicine have shown how mammalian brains create networks of tubes that transport toxins in and out of brain cells, similar to pneumatic tubes in factories and stores. This discovery, published in the journal Science, may advance understanding of the processes that lead to Alzheimer's
Diseases
Scientists at Johns Hopkins Medicine have made a groundbreaking discovery in the field of neuroscience, finding that brain cells produce 'pneumatic tubes' to transport toxic molecules, which may contribute to the development of Alzheimer's disease. This innovative research, published in the journal Science, sheds light on
Diseases
A new study has discovered a mechanism by which saturated fatty acids, such as palmitic acid (PA), contribute to the development of Alzheimer's disease (AD). The research, conducted at the National Autonomous University of Mexico (UNAM), found that PA induces insulin resistance, increases intracellular calcium and reactive oxygen
Medical research
Research on lecanemab, a monoclonal antibody that targets amyloid-beta aggregates, has increased significantly in recent years, with studies suggesting it may be a promising therapeutic for Alzheimer's disease. A new report compiled by researchers at the School of Medicine in Yangzhou, People's Republic of China, analyzed
Medical research
Major depressive disorder (MDD) with suspected non-Alzheimer's disease pathophysiology (SNAP) and MDD without SNAP exhibit distinct biological patterns, according to a new study. Researchers conducted cross-sectional analyses of 136 MDD patients, classified into SNAP and non-SNAP groups, and found significant associations among cerebral amyloid-b deposition, glucose metabolism, and
Alzheimer's disease
New research from Houston Methodist has made a significant discovery about the relationship between obesity and Alzheimer's disease. Scientists found that tiny messengers released by fat tissue, called extracellular vesicles, can carry harmful signals that accelerate the buildup of amyloid-b plaques in the brain. These vesicles can cross
