Proteins
Researchers at Western University conducted a study to evaluate the effectiveness of compound-specific nitrogen isotope analysis of amino acids (CSIA-AA) in reconstructing early childhood diets and detecting episodes of stress. The study, which analyzed nitrogen isotope compositions of fingernail keratin, found that proline delta N-15 was elevated in exclusively breastfed
Type 2 diabetes
Researchers have developed a novel approach to treating metabolic disorders by fusing a GLP-1 receptor agonist polypeptide with an antagonist glucose-dependent insulinotropic polypeptide receptor (GIPR) antigen binding protein. This fusion protein has shown promise in reducing body weight, improving insulin sensitivity, and promoting glucose tolerance. According to the patent application,
Amino acids
Researchers have developed a novel approach to treating metabolic disorders by fusing a GLP-1 receptor agonist polypeptide with an antagonist glucose-dependent insulinotropic polypeptide receptor (GIPR) antigen binding protein. This fusion protein has shown promise in reducing body weight, improving insulin sensitivity, and promoting glucose tolerance. According to the patent application,
Adults
Researchers have identified key associations between circulating amino acids and liver disease in a study published in the Journal of Diabetes and Metabolic Disorders. Conducted among Iranian adults aged 50 and over, the study found links between specific amino acids and an increased risk of non-alcoholic fatty liver disease (NAFLD)
Amino acids
Research scientists at the University of Texas Arlington have made a groundbreaking discovery in the field of biochemistry, developing a chemical labeling strategy for specific bioconjugation of aspartic (D) and glutamic (E) acid residues in proteins. This innovation is crucial for elucidating the roles of these residues in protein-protein interactions
Peptides
Researchers at Zhejiang Science Technical University have made significant breakthroughs in the field of cyclic peptides, leveraging the unique properties of sugar amino acids (SAAs) to design and develop next-generation therapeutics. Investigating the structural and functional advantages of SAAs, the team discovered that these hybrid molecules can overcome the limitations
Alzheimer's disease
Recent research has shed light on the role of AMPKa2 in transducing amino acid insufficiency signals to protein synthesis, providing new insights into the pathogenesis of Alzheimer's disease (AD). The study, conducted at Huashan Hospital in Shanghai, China, found that AMPKa2 specifically detects low amino acid levels and
Proteins
Research conducted at Maastricht University Medical Center in the Netherlands has uncovered significant effects of cold-water immersion on muscle protein synthesis rates after exercise. The study involved 12 young males who performed a single resistance exercise session, followed by water immersion in either cold (8°C) or thermoneutral (30°C)
Protein kinases
Recent research has shed light on the role of AMPKa2 in transducing amino acid insufficiency signals to protein synthesis, providing new insights into the pathogenesis of Alzheimer's disease (AD). The study, conducted at Huashan Hospital in Shanghai, China, found that AMPKa2 specifically detects low amino acid levels and
AIDS vaccines
Rockefeller University has made a groundbreaking discovery in the fight against HIV with the publication of a patented broadly neutralizing antibody that has the potential to prevent HIV infection. The patent, filed on March 6, 2024, and published online on September 30, 2025, describes a non-naturally occurring anti-HIV gp120 antibody
Amino acids
Researchers at the First Affiliated Hospital of Zhengzhou University have conducted a study to explore the changes in neurotransmitters in the brains of smokers. According to the study, the level of N-acetylaspartyl glutamate (NAAG) in the medial prefrontal cortex was found to be associated with daily smoking volume. The study
Amino acids
Research conducted by Tufts University has revealed a significant association between glutamate levels in the anterior cingulate cortex and disorganized speech in individuals with schizophrenia. The study, published in Biological Psychiatry Global Open Science, found that patients with lower glutamate levels demonstrated poor contextual sensitivity, a hallmark of disorganized speech.
