Antigenic determinants
Scientists at Xinjiang University have made a significant discovery in the diagnosis and monitoring of atherosclerosis, a deadly cardiovascular disease. By developing a triabody-based immunoassay, researchers have achieved a precise and sensitive tool for detecting the severity of atherosclerosis and tracking disease progression in patients. This breakthrough could lead to
Antigenic determinants
A team of researchers at the University of Science and Technology of China has made a breakthrough in designing a highly immunogenic multi-epitope subunit vaccine against the Dugbe virus, a serious tick-borne virus that poses a significant risk to cattle and human health. The innovative immunoinformatic techniques employed in this
Antigenic determinants
Researchers at Iowa State University have made significant progress in designing a next-generation vaccine against the Infectious Bronchitis Virus (IBV), which continues to threaten the poultry industry due to its rapid mutation and genetic diversity. The team developed AstraMEV, a predictive structural immunoinformatic platform that leverages genomic screening of 56
Antigenic determinants
Scientists at Xinjiang University have made a significant discovery in the diagnosis and monitoring of atherosclerosis, a deadly cardiovascular disease. By developing a triabody-based immunoassay, researchers have achieved a precise and sensitive tool for detecting the severity of atherosclerosis and tracking disease progression in patients. This breakthrough could lead to
Antigenic determinants
Research by scientists from the University of Minnesota has provided fresh insights into the function of Foxp3+ regulatory T cells in suppressing autoimmunity and responding to vaccination. The study, supported by the National Institutes of Health (NIH), discovered that these cells can fine-tune the primary response of conventional T cells
Antigenic determinants
Research by scientists from the University of Minnesota has provided fresh insights into the function of Foxp3+ regulatory T cells in suppressing autoimmunity and responding to vaccination. The study, supported by the National Institutes of Health (NIH), discovered that these cells can fine-tune the primary response of conventional T cells
Antigenic determinants
Researchers have developed a new approach to vaccine design that could provide effective protection against both Influenza A Virus and SARS-CoV-2. The study, published in Human Immunology, employed a bioinformatic approach to design a hybrid vaccine based on the epitopes of both viruses. This innovative method has the potential to
Antigenic determinants
Researchers at Huazhong University of Science and Technology have developed DNA vaccines encoding the spike protein of both the ancestral virus and Omicron variants, which demonstrated strong cross-reactive T cell responses in mice. The study found that only a limited number of mice vaccinated with the DNA vaccine targeting the
T cells
New research by a team of scientists from the University of Wisconsin Madison has made significant strides in predicting T cell receptor (TCR) activation. The study, which has been peer-reviewed, is based on a comprehensive database of 22,000 TCR-peptide pairs, centered around 25 immunogenic human and mouse epitopes, across
T cells
Researchers at Weill Cornell Medicine have found that engineered T cells have shown promise in cancer treatment, but may also recognize off-target epitopes, causing severe toxicities. The study, published in the journal Molecular Therapy, suggests that a genetic screen of 3,000 proteomic epitopes in the MHC-I ligandome uncovered off-target
T cells
Researchers at Weill Cornell Medicine have found that engineered T cells have shown promise in cancer treatment, but may also recognize off-target epitopes, causing severe toxicities. The study, published in the journal Molecular Therapy, suggests that a genetic screen of 3,000 proteomic epitopes in the MHC-I ligandome uncovered off-target
T cells
New research by a team of scientists from the University of Wisconsin Madison has made significant strides in predicting T cell receptor (TCR) activation. The study, which has been peer-reviewed, is based on a comprehensive database of 22,000 TCR-peptide pairs, centered around 25 immunogenic human and mouse epitopes, across
