American University of Beirut
Scientists at the American University of Beirut have conducted a study on the longitudinal T and B cell recall responses following vaccination with the Pfizer-BioNTech mRNA vaccine BNT162b2. The research, published in the Journal of Allergy and Clinical Immunology, found that the vaccine induces long-lasting neutralizing immunoglobulins and antigen-specific memory
Antigens
Scientists at the Heritage Institute of Technology in India have been investigating the effects of ultra-diluted Bryonia alba extract on modulating HMOX-1 gene expression to counteract the pathogenesis of SARS-CoV-2. Their research, published in the Journal of Virological Methods, reveals that Bry-alb can up-regulate the HMOX-1 gene, providing a potential
Antigens
Researchers in Portland, Oregon have made a significant breakthrough in the field of immunology by detailing the role of interferons in regulating MR1 transcription and antigen presentation. According to the study, interferons, such as IFNg, play a crucial role in stimulating MR1 expression and antigen presentation to MAIT cells, a
Antigens
Researchers at Memorial Sloan-Kettering Cancer Center have made significant progress in understanding the role of antigen-presenting cells (APCs) in mucosal immunity, tolerance, and inflammation. According to a recent study published in Nature Immunology, APCs play a crucial role in tailoring an appropriate immune response, ensuring both tolerance to innocuous antigens
Antigens
Researchers from Boston Children's Hospital have made significant strides in the field of translational medicine by developing a novel approach to treating autoimmune diseases. According to a recent study, OX40L-chimeric antigen receptor (CAR)-T cells have shown remarkable potential in controlling both allo- and autoimmune diseases. This breakthrough
Antigens
Researchers in Portland, Oregon have made a significant breakthrough in the field of immunology by detailing the role of interferons in regulating MR1 transcription and antigen presentation. According to the study, interferons, such as IFNg, play a crucial role in stimulating MR1 expression and antigen presentation to MAIT cells, a
Antigens
New research published in the Proceedings of the National Academy of Sciences has shed light on the intricate network of thymic hematopoietic antigen-presenting cells, revealing unexpected heterogeneity and tissue-specific properties. The study, conducted by researchers at the St. Vincent's Institute of Medical Research, has identified various cell lineages,
Antigens
Researchers from Imperial College London have made a significant breakthrough in the fight against malaria, developing a new diagnostic tool that can detect individuals who are capable of transmitting the disease to mosquitoes. According to the researchers, only sexual parasite forms, called gametocytes, which activate into gametes upon mosquito uptake
Elsevier Science Inc.
A team of researchers from the Laboratoire Hospitalier Universitaire de Bruxelles-Universitair Laboratorium Brussel (LHUB-ULB) in Brussels, Belgium, has published a new report on optimizing the diagnosis of pediatric group A streptococcus (GAS) pharyngitis. The study compared the sensitivity and specificity of rapid antigen detection tests (RADTs) and molecular tests with
Vaccines
Researchers from Hunan Agricultural University have presented a new study on the use of nanoparticles (NPs) to enhance antigenicity and induce high levels of humoral immune responses. According to the study published in the International Journal of Biological Macromolecules, the team designed three protein-based NPs derived from Ferritin, porcine circovirus
Vaccines
Scientists at Changchun University of Technology in Jilin, People's Republic of China, have made a groundbreaking discovery in the field of melanoma immunotherapy. By modifying chiral carbon dots with lactobionic acid, researchers created nanovaccines that exhibited enhanced antigen uptake and immune activities, leading to improved therapeutic effects in
Vaccines
Researchers at the University of Sao Paulo (USP) have made a significant breakthrough in COVID-19 vaccine development, using amino compounds-synthesized gold nanoparticles to deliver antigens. The study, published in Pharmaceutics, demonstrated that these nanoparticles can stimulate both innate and adaptive immune responses, and can be optimized for antigen presentation and
