Bedaquiline
Variability in Intrinsic Drug Tolerance in Mycobacterium tuberculosis Corresponds with Phylogenetic Lineage
A new study has shed light on the relationship between variability in intrinsic drug tolerance in Mycobacterium tuberculosis (Mtb) and its phylogenetic lineage. The research suggests that certain strains of Mtb are more intrinsically drug-tolerant and more readily evolve drug resistance. This has significant implications for the treatment of tuberculosis