Biochemistry

Biochemistry

Nucleotide-Specific RNA Conformations and Dynamics in Ribonucleoprotein Condensates Discussed in New Study

A recent study published in bioRxiv has shed light on the complex interactions between RNA and proteins in ribonucleoprotein (RNP) condensates. Researchers at Cornell University, led by Qingyue Hu, used contrast-variation solution X-ray scattering and ensemble-based structural modeling to characterize the conformational changes of flexible poly-A, poly-U, and poly-C single-stranded

Biochemistry

Perfluorooctanesulfonic Acid Found to Facilitate Choriocarcinoma Cell Migration in Dose-Dependent Manner

Research conducted by Maoxing Pan and colleagues at Jinan University, in collaboration with other institutions, has revealed that perfluorooctanesulfonic acid (PFOS) promotes the migration of choriocarcinoma cells in a dose-dependent manner. The study, published in Environmental Pollution, used the BeWo choriocarcinoma cell model to evaluate PFOS effects on trophoblast migration

Biochemistry

Cancer Immunotherapy Breakthrough: Researchers Develop Nanoparticles that Reprogram Macrophages and Activate Tumor-Fighting Immunity

Research conducted at the Institute for Biomedical Engineering in Tianjin, China, has led to the development of nanoparticles that can reprogram tumor-associated macrophages to fight cancer. The study, published in Biomaterials Science, shows that the nanoparticles can induce immunogenic cell death of tumor cells, activate dendritic cells, and initiate T