Pharmaceutical industry
Keryx Pharmaceuticals' colon cancer drug, perifosine, is expected to fail when the results of a phase III clinical trial are announced in early 2012. This prediction is shared by Dr. Mark Ratain, a University of Chicago oncologist and professor, who points to the company's market value and
Pharmaceutical industry
NeuroVive Pharmaceutical AB and to-BBB, a Dutch brain drug delivery company, have been awarded a €1 million grant through the Eureka Eurostars program for the joint development of therapies for stroke and other acute neurological conditions. This grant will support their preclinical development program on a potential new treatment for
Pharmaceutical industry
Spectrum Pharmaceuticals, a biotechnology company focused on hematology and oncology, has announced that it has achieved the target enrollment of its registrational trial for belinostat, a novel HDAC inhibitor, in relapsed or refractory peripheral T-cell lymphoma (PTCL). The trial, known as the BELIEF registrational study, is being conducted under a
Pharmaceutical industry
ImmunoGen, Inc. announced the submission of its Investigational New Drug (IND) application for IMGN529, a potential new treatment for B-cell malignancies, including non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukemia (CLL). IMGN529 targets CD37, a protein highly expressed in key NHL subtypes and CLL, and uses a CD37-targeting antibody
Pharmaceutical industry
Denosumab, a fully human monoclonal antibody, has been shown to reduce bone turnover markers and increase bone mass, density, and strength in ovariectomized cynomolgus monkeys. This research indicates that denosumab may be effective in preventing bone loss and reducing the risk of fractures in osteoporotic women. The study found that
Pharmaceutical industry
Inovio Pharmaceuticals has expanded its scientific advisory board with the appointment of two prominent leaders in the fields of vaccines and cancer immunotherapeutics. Dr. Thomas S. Edgington, Emeritus Professor of the Scripps Research Institute, and Dr. Philip D. Greenberg, Professor of Medicine (Oncology) and Immunology at the University of Washington,
Pharmaceutical industry
Warnex Inc., a life sciences company, has launched a new website for its PCA3 test for prostate cancer detection, available throughout Canada. The PCA3 test is a non-invasive, simple test performed on a urine sample that informs patients on their risk of having prostate cancer. According to Warnex, the PCA3
Pharmaceutical industry
Mipomersen, an experimental therapy, has demonstrated significant reductions in low-density lipoprotein cholesterol (LDL-C) and lipoprotein(a) (Lp(a)) levels in patients with familial hypercholesterolemia (FH). These results were presented at the 79th European Atherosclerosis Society (EAS) Congress, where two phase 3 studies showed that mipomersen effectively lowered Lp(a) levels,
Pharmaceutical industry
Micromet, Inc. has entered into a collaboration agreement with Amgen Inc. for the research of BiTE antibodies against three undisclosed solid tumor targets. Amgen will have the right to pursue development and commercialization of BiTE antibodies against up to two of these targets. The collaboration is expected to bring in
Pharmaceutical industry
Genentech, a member of the Roche Group, announced that a Phase III study (BRIM3) showed vemurafenib significantly improved overall survival (OS) in people with previously untreated BRAF V600 mutation-positive metastatic melanoma, compared to chemotherapy. In the study, the risk of death was reduced by 63 percent for people who received
Pharmaceutical industry
Genentech, a member of the Roche Group, announced that a Phase III study (BRIM3) demonstrated vemurafenib significantly improved overall survival in patients with previously untreated BRAF V600 mutation-positive metastatic melanoma compared to chemotherapy. The study showed a 63% reduction in the risk of death for patients who received vemurafenib versus
Pharmaceutical industry
Seven Summits Research, an independent investment research group, has issued critical PriceWatch Alerts for five top stocks: Amgen Inc. (Nasdaq: AMGN), Boeing Co. (NYSE: BA), Goldcorp Inc. (NYSE: GG), American Tower Corp. (NYSE: AMT), and GT Solar International, Inc. (Nasdaq: SOLR). The alerts aim to provide concise, detailed strategies for
