Cancer research
A clinical trial at the Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, aims to assess the effectiveness of artificial intelligence (AI) in supporting radiologists in interpreting mammograms. Led by Jose Net, M.D., the study will involve hundreds of thousands of mammograms and
Cancer research
Researchers from the National Institute of Health and Medical Research have announced encouraging findings from the ICARUS-BREAST 01 study, which evaluated the efficacy and safety of patritumab deruxtecan (HER3-DXd) in patients with hormone receptor-positive metastatic breast cancer. The study involved 99 patients who had already received multiple treatments, including hormone
Cancer research
Researchers at the University of Michigan Rogel Cancer Center are nearing the recruitment phase for a Phase 2 clinical trial examining the effects of ovarian function suppression for breast cancer patients. The trial, led by principal investigator Norah L. Henry, aims to compare the efficacy of leuprolide at different doses
Cancer research
A new study has shed light on the alarming rise in breast cancer incidence and mortality rates among individuals aged 55 and above worldwide. The research, conducted by a team of investigators from Southern Medical University in Guangzhou, People's Republic of China, reveals that breast cancer remains a
Cancer research
According to a recent study published in the Journal of the American Nutrition Association, researchers at Wroclaw Medical University in Poland have found that phytoestrogens, found in foods such as soy products and flaxseed, may help reduce the risk of breast cancer in postmenopausal women. The study, titled "Comprehensive
Cancer research
Researchers at Huashan Hospital Affiliated to Fudan University have initiated a clinical trial to investigate the occurrence and associated factors of postoperative upper limb dysfunction in breast cancer patients, with the aim of providing a scientific basis for developing personalized intervention strategies. The study will utilize wearable devices monitoring shoulder
Cancer research
Scientists at First Jining People's Hospital in Jining, People's Republic of China, have made a groundbreaking discovery in the fight against breast cancer. According to a recent study, a DNA tetrahedron (DT) nanostructure has been successfully used to co-deliver shikonin and CpG oligonucleotide, achieving chemoimmunotherapy of
Cancer research
Researchers from the University of Malaya, in collaboration with Cancer Research Malaysia, have conducted a phase II clinical trial to evaluate the efficacy of pembrolizumab monotherapy in metastatic HER2-negative breast cancer patients with germline APOBEC3B deletion. The study, published in The Lancet Regional Health - Western Pacific, found that pembrolizumab
Cancer research
Researchers at Universitatsklinikum Erlangen, in collaboration with various international institutions, have conducted a study to investigate the prognostic impact of the choice of chemotherapy after first-line CDK4/6 inhibitor therapy in patients with metastatic hormone receptor-positive, HER2-negative breast cancer. The study, published in the European Journal of Cancer, analyzed data
Cancer research
Researchers from Monash University have successfully demonstrated the feasibility of high-energy propagation-based computed tomography for human adult-scale lung imaging using the Australian Synchrotron's Imaging and Medical Beamline. This novel technique offers a significant advancement in medical imaging, allowing for lower radiation doses and improved diagnostic accuracy for lung
Cancer research
A recent study published in Biochimica Et Biophysica Acta-molecular Cell Research has shed light on the role of prolyl isomerase Pin4 in the development of ERα-positive breast cancers. Researchers at Hiroshima University found that Pin4 regulates ERα transcriptional activity and is essential for the proliferation of ERα-positive breast cancer cells.
Cancer research
Researchers from Quaid-I-Azam University have made significant progress in understanding breast cancer, identifying key biomarkers, and developing novel therapeutic agents. The study, published in the Journal of Chemical Information and Modeling, employed network-based gene expression profiling to identify differentially expressed genes (DEGs) as potential biomarkers in breast cancer. The analysis
