Cancer research
A recent study published in Frontiers in Pharmacology has shed new light on the molecular pathogenesis of lung adenocarcinoma (LUAD), a type of non-small cell lung cancer. The research, conducted by a team of scientists from Zhejiang University School of Medicine, has identified two epigenetic-autophagy genes, KDM6B and KANSL1, as
Cancer research
Researchers from the Department of Infectious Diseases have shed new light on the expression heterogeneity of ferroptosis-related genes in hepatocellular carcinoma (HCC). This study, published in the journal Discover Oncology, utilized bioinformatics analysis, weighted gene co-expression network analysis (WGCNA), and single-cell RNA sequencing data to identify key ferroptosis-related gene modules
Cancer research
Researchers from Sun Yat-Sen University have conducted a study to examine the expression of collagen genes in bladder cancer and develop a nomogram to predict overall survival for patients diagnosed with the disease. The study aimed to investigate the correlation between collagen genes and overall survival in bladder cancer patients
Genetic research
Research conducted by a team of scientists from the Federal University of Ceara has made a significant breakthrough in cancer gene therapy by developing a targeted delivery system for the photosensitizer chloroaluminum phthalocyanine (ClAlPc). The study aimed to address the challenges associated with ClAlPc's lipophilic nature and aggregation
Genetic research
Investigations into the potential of gold nanoparticles in cancer gene therapy have yielded promising results. Researchers at Istanbul Medipol University have published a new report highlighting the advantages of gold nanoparticles in biomedical applications, including cancer therapy, drug delivery, and gene silencing. According to the study, gold nanoparticles possess unique
Genetic research
Investigators at the Korea Institute of Science and Technology, Seoul, South Korea, have developed a novel hybrid gene delivery platform combining adeno-associated virus (AAV)-mediated expression of receptor-interacting kinase 3 (RIPK3) with manganese dioxide-polyethyleneimine (MnO-PEI) to induce necroptosis and immunogenic cell death (ICD) in cancer therapy. The platform reportedly offers
Cancer research
Researchers at the Chinese Academy of Medical Sciences have made a significant breakthrough in cancer gene therapy, discovering a novel approach to sensitize hepatocellular carcinoma (HCC) to radiotherapy. The study, published in Advanced Science, found that dual-targeted nanovesicles (CALT-GM-NVs) can induce cancer stem-like cell differentiation, reducing radiotolerance and improving radiotherapy
Cancer research
Researchers from Oxford University have discovered a new function of platelets, revealing that they capture and store fragments of DNA in the bloodstream, including fetal DNA and mutated DNA from cancer cells. This finding suggests that analysing DNA within platelets could improve early cancer detection and prevention by revealing '
Genetic research
A recent study published in Obstetrics & Gynecology Science has shed light on the awareness and knowledge of breast cancer susceptibility gene (BRCA) mutations among family members of women diagnosed with epithelial ovarian or fallopian tube cancer. The research, conducted by a team of researchers at Chiang Mai University, aimed
Cancer research
Researchers at the University of Washington have conducted a comprehensive review of dissolving microneedles for nucleic acid delivery, highlighting their potential in cancer gene therapy. The study, published in Acta Biomaterialia, analyzed existing preclinical data to identify correlations between microneedle form and function, revealing that 83% of studies showed equivalent
Genetic research
Researchers at Ningbo University have made a groundbreaking discovery in the field of cancer research, identifying 18 Myb gene family members in the economically important red alga Gracilariopsis lemaneiformis. The study, published in Marine Biotechnology, reveals that these genes play a crucial role in high-temperature stress, salicylic acid, methyl jasmonate,
Genetic research
Research emerging from Nanchang, People's Republic of China, highlights the challenges faced by traditional cancer treatment modalities such as surgery, chemotherapy, and radiotherapy. Amidst the growing global incidence of cancer, scientists have been working to develop more effective treatment strategies. In a recent study, researchers from Jiangxi Science
