Cancer genetics

Cancer research

Advances in Cancer Gene Therapy: Bisphosphonate-Based Drug Delivery Systems

Research from Tarbiat Modares University in Tehran, Iran, has made significant progress in cancer gene therapy, particularly in the development of bisphosphonate-based drug delivery systems. These systems target bone-mineral matrices, inhibiting excessive osteoclast activity associated with various bone disorders. The study highlights the potential of these systems in concentrating therapeutic

Cancer

New Insights into Doxorubicin Therapy: Research Reveals Role of NETs in Cardiotoxicity

Research conducted at Sun Yat Sen University Cancer Center has unveiled a crucial link between neutrophil extracellular trap (NET) DNA and cardiotoxicity in patients undergoing anthracycline-containing treatment. The study discovered that doxorubicin, a common chemotherapy drug, induces HMGB1-dependent cardiac NET formation, promoting cardiac remodeling and dysfunction. The researchers identified a

Cancer

Advancements in Cancer Gene Therapy: Optimizing Photosensitizers for Enhanced Efficacy

Researchers from the Guangdong University of Technology have made significant progress in optimizing photosensitizers for cancer gene therapy. By developing new structural modifications, nanocarrier systems, and stimulus-responsive designs, the team aims to enhance the stability, specificity, and responsiveness of these compounds. According to the study, key strategies include chemical modifications,