Cancer
A recent study published in the JMIR Cancer journal has found that publicly available information on genomic medicine at National Cancer Institute-designated cancer centers (NCI-CCs) in the United States is often lacking. Despite efforts to provide personalized care and incorporate genetic testing, many centers fail to publicly communicate their efforts
Cancer
Scientists at Instituto Superior Tecnico have made significant strides in cancer gene therapy by developing novel dendrimers that demonstrate intrinsic anticancer activity. According to the research, these dendrimers, specifically PUREG4-OEI48 and PUREG4-OCEI24, disrupt cell membrane integrity, interact with mitochondria, and induce cell death by promoting apoptosis. The findings indicate that
Cancer genetics
Researchers from the University of Texas Southwestern Medical Center have developed a novel method, Categorical and Phenotypic Image Synthetic Learning (CATphishing), to address the challenges of traditional federated learning in medical imaging. This innovative approach uses Latent Diffusion Models to generate synthetic multi-contrast three-dimensional magnetic resonance imaging data, eliminating the
Cancer genetics
Researchers at Kyushu University have identified zinc finger protein 282 (ZNF282) as a novel gene that contributes to the progression of colorectal cancer (CRC). According to a study published in Cancer Science, high expression of ZNF282 was associated with distant metastasis and poor prognosis in CRC patients. The study also
Cancer genetics
New research has shed light on the shortcomings of traditional chemotherapy and the potential of targeted drug delivery systems (DDS) for enhanced cancer treatment. According to a study published in the Journal of Drug Delivery Science and Technology, cancer remains a major global health concern, necessitating the development of novel
Antineoplastic agents
A new review published in The Kaohsiung Journal of Medical Sciences highlights the potential of nanotechnology in transforming skin cancer treatment. Researchers from Chang Gung University of Science and Technology, led by Ching-Yun Hsu, have summarized the recent advances in nanocarrier-based approaches for skin cancer therapy. The study emphasizes the
Cancer
Researchers at the State Research Center, in collaboration with international colleagues, have made a significant contribution to the field of cancer gene therapy. According to a recent study published in Acta Naturae, they have engineered targeted nanoliposomes capable of delivering large quantities of boronophenylalanine into cancer cells. This innovation may
Cancer
Researchers at the State Research Center, in collaboration with international colleagues, have made a significant contribution to the field of cancer gene therapy. According to a recent study published in Acta Naturae, they have engineered targeted nanoliposomes capable of delivering large quantities of boronophenylalanine into cancer cells. This innovation may
Cancer
Researchers from Weill Cornell Medicine and the University of Adelaide have developed a revolutionary tool, GoT-Multi, that allows for the simultaneous tracking of multiple gene mutations and recording of gene activity in individual cancer cells. This next-generation technology overcomes the limitations of its predecessor, GoT, and can process large numbers
Genetic research
Research from Brown University sheds light on the first prospective oncologic outcomes of radiotherapy decisions guided by a 12-gene molecular assay, the DCIS score (DS). The study focused on breast ductal carcinoma in situ (DCIS), a condition that requires personalized treatment due to its variable natural history. The study aimed
Cancer research
A multi-institutional study, co-authored by Danny Reinberg, Ph.D., has shed light on a genetic mechanism in ants that could have significant implications for understanding gene regulation and cancer biology. The unique process that allows ants to pinpoint specific scents may also occur in human cells, particularly in cancer, where
Genetic research
A multi-institutional study, led by researchers at the University of Miami Miller School of Medicine's Sylvester Comprehensive Cancer Center, has made a groundbreaking discovery in the field of cancer biology. The study reveals a unique genetic mechanism in ants that could have far-reaching implications for understanding gene regulation
