Biochemistry
A study published in Functional & Integrative Genomics has shed light on the relationship between liver metastasis in colon cancer and clinicopathological factors, as well as the underlying molecular mechanisms. Researchers from Zhengzhou University identified cardiolipin synthase 1 (CRLS1) as a hub gene associated with liver metastasis in colon cancer,
Biochemistry
A study published in Functional & Integrative Genomics has shed light on the relationship between liver metastasis in colon cancer and clinicopathological factors, as well as the underlying molecular mechanisms. Researchers from Zhengzhou University identified cardiolipin synthase 1 (CRLS1) as a hub gene associated with liver metastasis in colon cancer,
Cancer metastasis
The European Society for Medical Oncology (ESMO) 2025 Congress saw the presentation of data from the Phase 1b/2 OrigAMI-4 study evaluating the efficacy and safety of subcutaneous amivantamab monotherapy in patients with human papillomavirus (HPV)-unrelated, recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) after
Cancer research
Research published in European Urology Open Science has highlighted the importance of real-world evidence in guiding treatment decisions for metastatic hormone-sensitive prostate cancer (mHSPC). The study, conducted by an international team of researchers, analyzed health records and insurance claims from over 69,000 patients with mHSPC across eight European and
Big data
Research published in European Urology Open Science has highlighted the importance of real-world evidence in guiding treatment decisions for metastatic hormone-sensitive prostate cancer (mHSPC). The study, conducted by an international team of researchers, analyzed health records and insurance claims from over 69,000 patients with mHSPC across eight European and
Adenocarcinoma
Researchers at East Tennessee State University have reported a rare case of gastric adenocarcinoma metastasis to the skin, highlighting the importance of urgent biopsy and timely staging in patients with known or suspected malignancy. The case study describes an 80-year-old man with stage IV gastric adenocarcinoma who developed rapidly enlarging
Adenocarcinoma
Researchers at East Tennessee State University have reported a rare case of gastric adenocarcinoma metastasis to the skin, highlighting the importance of urgent biopsy and timely staging in patients with known or suspected malignancy. The case study describes an 80-year-old man with stage IV gastric adenocarcinoma who developed rapidly enlarging
Adenocarcinoma
Researchers at East Tennessee State University have reported a rare case of gastric adenocarcinoma metastasis to the skin, highlighting the importance of urgent biopsy and timely staging in patients with known or suspected malignancy. The case study describes an 80-year-old man with stage IV gastric adenocarcinoma who developed rapidly enlarging
Cancer metastasis
Research from the Department of Orthopaedic Surgery in Osaka, Japan, investigated the effects of spinal surgery on the activities of daily living (ADL) in patients with metastatic spinal tumors. According to the study, which analyzed 404 symptomatic patients who underwent surgical treatment, spinal surgery can improve ADL in patients with
Antineoplastic agents
A new study conducted by researchers at Dokuz Eylul University in Izmir, Turkey, has uncovered a significant association between serum uric acid levels and survival outcomes in patients with metastatic renal cell carcinoma treated with targeted therapies. The research, published in the journal BMC Cancer, analyzed the prognostic importance of
Cancer research
Researchers at Bayer HealthCare Pharmaceuticals Inc. have published a study on the long-term responses of patients with metastatic colorectal cancer (mCRC) treated with regorafenib. The study, published in the journal Cancers, analyzed a database of 2444 patients who initiated regorafenib monotherapy between 2013 and 2023. The research found that patients
Cancer research
Research findings presented in a new report from the Shanxi Province Cancer Hospital in Taiyuan, People's Republic of China, indicate that the combination of serplulimab with platinum-based chemotherapy yields promising results in treating extensive-stage small cell lung cancer (ES-SCLC) liver metastases. The study involved 30 patients with ES-SCLC
