Cancer
A study published in the British Journal of Clinical Pharmacology has found that proton pump inhibitors (PPIs) are associated with shorter progression-free survival in patients with advanced gastric cancer receiving ramucirumab, a vascular endothelial growth factor receptor 2 (VEGFR2)-targeting monoclonal antibody, plus paclitaxel or nab-paclitaxel. Researchers from the University
Cancer
Research conducted by the University of Bologna, Italy, has identified a significant correlation between the loss of human leukocyte antigen class I (HLA-I) expression and poor prognosis in endometrial cancers, particularly in the no specific molecular profile (NSMP) subtype. The study, published in the journal Histopathology, assessed HLA-I expression in
Cancer
A new study published in the World Journal of Gastrointestinal Surgery has shed light on the importance of gut microbiota modulation in postoperative depression management for gastric cancer patients. Researchers from Hubei University of Medicine have discovered that triple viable bacteria combined with mirtazapine significantly reduces depression scores and improves
Cancer
Peter MacCallum Cancer Centre, a leading cancer centre in Australia, is working to improve the cultural safety of First Nations people receiving cancer care through two new projects. The projects aim to foster new connections between healthcare providers and Aboriginal-led organisations, ultimately supporting better outcomes for First Nations patients. The
Cancer research
A new study from Chang Gung Memorial Hospital Linkou in Taoyuan, Taiwan, has shed light on the effects of metformin on rectal cancer patients undergoing neoadjuvant chemoradiotherapy. The research, published in Scientific Reports, involved a retrospective analysis of 89 patients with locally advanced rectal cancer, of whom 56 were metformin
Cancer research
Malnutrition remains a significant concern for critically ill patients, especially those undergoing gastrointestinal surgery. Researchers at University Gadjah Mada in Yogyakarta, Indonesia have highlighted the importance of adequate nutritional therapy in preventing malnutrition in such cases. A recent study published in Jurnal Anestesiologi Indonesia, the official journal of the Faculty
Cancer research
Akeso, Inc. has achieved a significant milestone in the fight against gastric cancer, enrolling and dosing the first patient in the pivotal Phase III clinical trial (AK104-310/COMPASSION-33) evaluating cadonilimab for the perioperative treatment of resectable gastric/gastroesophageal junction (G/GEJ) adenocarcinoma. This study aims to improve radical resection rates,
Cancer research
Researchers at Fudan University Shanghai Cancer Center have discovered a new predictive tool for personalized therapy in colorectal cancer (CRC) patients. By analyzing the methylation status of septin 9 (mSEPT9), a research team led by Han Shan was able to identify a significant association between mSEPT9 positivity and clinicopathological characteristics
Cancer
Research conducted at the Meshalkin National Medical Research Center has highlighted the complexities of radiation-induced heart disease in patients with chest cancer. According to the study, radiation therapy can cause a range of heart-related complications, including pericarditis, cardiomyopathy, coronary artery disease, acquired valvular heart disease, and arrhythmias. The study aimed
Cancer research
According to a recent study published in Anticancer Research, investigators at the University of Lubeck have developed a risk score for radiation pneumonitis (RP) in elderly lung cancer patients. This score was compared to an existing tool created for patients of any age and was found to be highly accurate
Cancer
InhaleRx Ltd. has registered a Phase 2 clinical trial with the Australian New Zealand Clinical Trials Registry (ANZCTR) to investigate the efficacy and safety of IRX211a for the treatment of breakthrough cancer pain in opioid-tolerant patients. The study aims to determine whether IRX211a can provide fast and effective pain relief
Cancer research
New research has shed light on the diagnostic accuracy of patients presenting with unexpected weight loss in Australian general practices. By analyzing data from the Patron primary care database, linked to hospital admissions data and the Victorian Cancer Registry, researchers from the University of Oxford have calculated positive predictive values
