Cancer research
Actuate Therapeutics, Inc. has initiated a Phase 1b trial to evaluate the safety and efficacy of a novel combination of its lead investigational drug, elraglusib, with Incyte's PD-1 inhibitor, retifanlimab, and modified FOLFIRINOX (mFOLFIRINOX) as frontline therapy in advanced pancreatic adenocarcinoma. The trial, led by Anwaar Saeed, MD,
Cancer research
Caris Life Sciences has published a groundbreaking study in Nature Communications demonstrating the potential of AI-based image analysis to transform immunotherapy decisions and precision oncology. The study, which analyzed hematoxylin and eosin (H&E) images from over 35,000 patients, showed that Caris' AI model can improve the
Cancer research
Recent research conducted at the University of Texas Medical Branch has shed light on the connection between prolonged use of immunosuppressive drugs and an increased risk of cancer in transplant patients. A team of investigators studied the risk of cancer associated with five commonly used immunosuppressive drugs: tacrolimus, cyclosporin, sirolimus,
Cancer
A study published in the journal Vascular has explored the impact of preoperative disseminated cancer on the 30-day outcomes of endovascular aneurysm repair (EVAR) for non-ruptured abdominal aortic aneurysms (AAAs). Researchers from George Washington University analyzed data from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database
Cancer
Oncologists in China are cautiously embracing the potential benefits of artificial intelligence (AI)-driven chatbots in cancer patient education, but numerous concerns about liability, misinformation, and data security risks are hindering wider adoption. A recent study involving 24 oncologists from four hospitals in Southwest and East China found that while
Cancer
A new study, "The Invisible Tsunami," has highlighted the devastating impact of toxic chemicals present in our air, food, and water. Researchers have found that more than 3,600 synthetic chemicals are present in human bodies globally, with 80 of these chemicals feared to be especially dangerous. The
Cancer
Air Vice-Marshal Fin Monahan, a 57-year-old father of three, was diagnosed with myeloma in 2009 while serving in the RAF. He has since relapsed twice, but thanks to whole-body MRI scans, his cancer was detected much earlier than would have been possible with a traditional CT scan. This cutting-edge treatment
Cancer research
Patients with cancer often struggle with anxiety and depression, which can significantly impact their quality of life. Researchers at Sultan Idris Education University in Malaysia have conducted a systematic review to investigate the effectiveness of music therapy and Tai Chi exercise in alleviating these symptoms. The study aimed to evaluate
Cancer research
A pioneering study led by the Break Through Cancer team has shed new light on the recalcitrant nature of ovarian cancer, which often recurs despite initial treatment. Using minimally invasive surgery and blood tests, researchers discovered that nearly half of patients who appeared cancer-free on scans still harbored hidden cancer
Cancer research
Researchers at the Guangzhou Medical University Cancer Hospital in China have initiated a clinical trial to develop a precision intervention system for nasopharyngeal cancer (NPC) patients undergoing radiotherapy. The study aims to establish a nutritional symptom network model using multi-source data and create a tailored response plan to optimize nutritional
Cancer research
A recent study conducted by researchers at Kyungpook National University in South Korea has found a correlation between higher body mass index (BMI) and the severity of chemotherapy-induced peripheral neuropathy (CIPN) in patients with ovarian cancer. The study, which was published in the Journal of Clinical Medicine, retrospectively analyzed data
Cancer research
NRG Oncology has listed a Phase 3 clinical trial, ARCHER, designed to study the effectiveness of adaptive radiation and chemotherapy in treating muscle invasive bladder cancer. The trial aims to recruit 486 participants from the USA and compares the impact of ultra-hypofractionated radiation therapy with standard hypofractionation, alongside chemotherapy, on
