Hepatocellular carcinoma
Researchers at the First Affiliated Hospital of Sun Yat-sen University in Guangzhou, People's Republic of China, have made significant discoveries in the field of liver cancer treatment. The study, published in Liver Cancer, aimed to evaluate the outcomes of patients with initially unresectable hepatocellular carcinoma (HCC) who received
Liver cirrhosis
Research from St. Louis University indicates that Branched-Chain Amino Acid (BCAA) supplementation significantly reduces the risk of liver cirrhosis complications, including hepatic encephalopathy, spontaneous bacterial peritonitis, and falls. The study, which utilized a propensity score-matched multicenter retrospective cohort, found that patients receiving BCAA supplementation had lower rates of the composite
Cancer research
Research at University Hospital Hamburg Eppendorf in Hamburg, Germany, has shed light on the current practices in staging intermediate-risk prostate cancer patients. According to the study, current European Association of Urology (EAU) guidelines provide only a weak recommendation for staging in selected intermediate-risk prostate cancer patients. However, data on the
Cancer research
Researchers at Hebei General Hospital in Hebei, People's Republic of China, have made significant discoveries about the role of ammonia-induced cell death (AID) in gastric adenocarcinoma (STAD). Their study, published in Cancer Cell International, has provided new insights into the mechanisms of AID and its impact on immune
Non-small cell lung cancer
Researchers at Nanchang University have made a significant breakthrough in the diagnosis of non-small cell lung cancer (NSCLC) by developing a non-invasive method to predict epidermal growth factor receptor (EGFR) gene mutations. This method uses multi-parameter CT perfusion imaging (CTPI) to analyze blood volume, transit time, and perfusion surface in
Cancer research
Investigators at Chiba Cancer Center Research Institute have published a new report on the effectiveness of pathogenesis-based treatment strategies for brain metastases from non-small cell lung cancer. The research suggests that more than half of brain metastases in patients with non-small cell lung cancer are diagnosed at the time of
Cancer research
Current research on the treatment of gastric cancer has yielded promising results, with early oral feeding (EOF) after gastrectomy showing significant reductions in hospital stay and improvements in recovery. According to a systematic review and meta-analysis conducted by researchers at Kazan Federal University, EOF was found to be a safe
Cancer research
Researchers at the People's Hospital of Liaoning Province have discovered a link between the protein RHOT1 and gastric cancer progression. The study, published in the International Journal of Oncology, found that RHOT1 regulates mitochondrial dynamics and energy metabolism, and its silencing reduced mRNA expression by 59.75% and
Cancer research
Researchers at the University of British Columbia have made significant progress in the field of cancer treatment, revealing that nearly half of humanity will develop cancer in their lifetime. Current therapies, particularly chemotherapeutic drugs, face significant challenges due to the lack of tissue-specific delivery. To address this issue, lipid-based nanoparticles
Cancer research
Research findings from the University of Hong Kong have shed light on the significance of glycaemic control in preventing pancreatic cancer in patients with type 2 diabetes. The study, published in Gut, a peer-reviewed journal, aimed to investigate the effects of glycaemic control on pancreatic cancer development in patients with
Cancer research
A new study has shed light on the genetic alterations and microRNAs (miRNAs) that play a crucial role in lung cancer progression. According to the research, lung cancer is the most frequently diagnosed type of cancer worldwide, with key genetic alterations involving driver gene mutations that significantly enhance cancer aggressiveness.
Cancer research
Researchers at the Yale University School of Medicine have made a significant breakthrough in understanding the role of asparagine-linked glycosylation protein 1 (ALG1) in lung cancer progression. According to a newly published study, ALG1 promotes aggressive phenotypes of lung adenocarcinoma cells by modulating N-linked glycosylation and endoplasmic reticulum (ER)-stress
