Prostate cancer
Research conducted in Yogyakarta, Indonesia, by investigators from the Faculty of Medicine has shed light on the differences in pathological outcomes and safety between subcapsular orchiectomy and pharmacological androgen deprivation therapy (ADT) for prostate cancer management. A systematic search was conducted on various databases, and 13 studies meeting the inclusion
Cancer research
Research conducted by scientists at Bengbu Medical University has shed new light on the role of long non-coding RNA (lncRNA) FEZF1-AS1 in non-small cell lung cancer (NSCLC) tumorigenesis and ferroptosis. The study found that FEZF1-AS1 promotes NSCLC progression through suppressing ferroptosis by activating the tumor necrosis factor-alpha (TNF-a)/nuclear factor-kappa
Lung cancer
Asian Americans are at a higher risk of being diagnosed with lung cancer at a distant stage of the disease and are less likely to receive smoking cessation advice compared to the general US population. A recent study conducted by researchers from the University of Massachusetts Boston aimed to investigate
Cancer research
A new study published in European Urology Oncology has shed light on the treatment landscape of metastatic hormone-sensitive prostate cancer (mHSPC). The researchers aimed to describe treatment trajectories and clinical outcomes in a large, multicenter real-world data (RWD) cohort under the PIONEER project. The study analyzed data from eight European
Cancer research
Researchers at the First Affiliated Hospital of Sun Yat-sen University in Guangzhou, People's Republic of China, have made significant discoveries in the field of liver cancer treatment. The study, published in Liver Cancer, aimed to evaluate the outcomes of patients with initially unresectable hepatocellular carcinoma (HCC) who received
Cancer research
Researchers from the First Affiliated Hospital of Anhui Medical University have developed a novel NLR-based prognostic model that effectively stratifies hepatocellular carcinoma (HCC) patients by survival risk. This study aimed to evaluate the prognostic value and biological function of NLR genes in HCC. The researchers analyzed transcriptomic and clinical data
Cancer research
Researchers at Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Taiwan, have published a study evaluating the oncological outcomes of external beam radiation therapy (EBRT) versus high-intensity focused ultrasound (HIFU) in patients with stage II prostate cancer. The study retrospectively reviewed patients from the Chang Gung Research Database spanning
Cancer research
Researchers at AstraZeneca have made a groundbreaking discovery in the treatment of prostate cancer, revealing that a combination of poly(ADP-ribose) polymerase inhibitors (PARPi) with androgen receptor (AR) pathway inhibitors (ARPi) can significantly improve outcomes for patients with metastatic, castration-resistant prostate cancer. This study, published in NAR Cancer, found that
Cancer research
Researchers from the IRCCS Foundation National Cancer Institute in Milan, Italy, have published a study in The Oncologist, a leading oncology journal, highlighting the superiority of dual PD-1/CTLA-4 blockade with nivolumab and ipilimumab in treating metastatic colorectal cancer (mCRC) patients with deficient mismatch repair (dMMR) and/or microsatellite instability-high
Cancer research
A recent study published in Neuro-Oncology has identified novel genomic associations with brain metastasis and progression in colorectal cancer, offering a potential basis for personalized clinical management. Researchers at Memorial Sloan-Kettering Cancer Center analyzed next-generation sequencing data from patients with colorectal cancer to identify genomic features associated with brain metastasis
Cancer research
A groundbreaking study on personalized medicine for cancer prevention has been published, highlighting the importance of electronic health records (EHRs) in early detection. Researchers at Harvard College developed a prediction model using data from Mass General Brigham's EHR to identify high-risk individuals for non-small cell lung cancer (NSCLC)
Cancer research
Current research on the treatment of gastric cancer has yielded promising results, with early oral feeding (EOF) after gastrectomy showing significant reductions in hospital stay and improvements in recovery. According to a systematic review and meta-analysis conducted by researchers at Kazan Federal University, EOF was found to be a safe
