Cancer research
Researchers at Gifu University Graduate School of Medicine have made a significant breakthrough in the treatment of prostate cancer, particularly in cases of metastatic castration-sensitive prostate cancer (mCSPC). A recent study published in Cancer Reports has demonstrated the efficacy of a combination therapy involving androgen receptor signaling inhibitors, denosumab, and
Cancer research
Researchers at Lund University have made a significant discovery in the fight against cancer, identifying Leucine-Rich Repeat Containing 15 (LRRC15) as a promising biomarker and target for cancer therapy. According to their study, published in Signal Transduction and Targeted Therapy, transforming growth factor-b (TGFb) induces the expression of LRRC15 specifically
Cancer research
Scientists at The Institute of Cancer Research in London have made a breakthrough discovery in treating advanced prostate cancer. They have found that a combination of two targeted drugs could slow down tumour growth and kill cancer cells in up to two-fifths of patients with this type of cancer. The
Cancer research
Scientists at The Institute of Cancer Research in London have made a breakthrough discovery in treating advanced prostate cancer. They have found that a combination of two targeted drugs could slow down tumour growth and kill cancer cells in up to two-fifths of patients with this type of cancer. The
Cancer research
A recent study has found a significant association between the hospitalist system and reduced in-hospital mortality rates among patients with cancer. The research, conducted by a team of scientists from Yonsei University in Seoul, South Korea, analyzed data from the Korean National Health Insurance Service Cohort Database and found that
Cancer research
During Breast Cancer Awareness Month, the American Cancer Society is proud to highlight the groundbreaking work of Dr. Steven Katz, professor of health management and policy at the University of Michigan. Dr. Katz's research has focused on expanding access to genetic counseling and testing for breast cancer patients
Cancer research
A recent study published in the European Heart Journal - Cardiovascular Imaging has shed light on the sex-specific prognostic value of automated epicardial adipose tissue quantification on serial lung cancer screening chest computed tomography. The research, conducted by investigators from Massachusetts General Hospital, analyzed data from 24,008 heavy-smoking participants
Cancer research
Scientists at the Affiliated Hospital of Nantong University, Jiangsu, People's Republic of China, have conducted a study on the molecular characteristics of Consensus Molecular Subtype 4 (CMS4) of colorectal cancer (CRC). According to their research, CMS4 CRC is characterized by TGF-b activation and is often accompanied by metastasis
Cancer research
Researchers at the Tianjin University of Traditional Chinese Medicine have made a groundbreaking discovery in the field of oncology, leveraging the power of traditional Chinese medicine to enhance the efficacy of PD-1 antibody treatment in colorectal cancer. The study, published in the journal Phytomedicine, reveals that Zhenqi Fuzheng Granule (ZQFZ)
Cancer research
Research conducted at the Department of Oncology at Liuzhou People's Hospital in China has shed new light on the complex roles played by tumor-associated macrophages (TAMs) in colorectal cancer (CRC). According to a study published in the Journal of Inflammation Research, the researchers identified three distinct TAM subtypes
Cancer research
French researchers have made a significant breakthrough in the treatment of prostate cancer by discovering that inhibiting histone H4-lysine 20 (H4K20) methyltransferases SUV4-20H1 and SUV4-20H2 can induce synthetic lethality in combination with the topoisomerase II poison etoposide. This epigenetic therapy targets the SUV4-20H enzymes, which play a crucial role in
Cancer research
Pancreatic cancer, characterized by a profoundly immunosuppressive tumor microenvironment, has a poor prognosis. Researchers at the Sichuan Cancer Hospital studied the role of dendritic cells (DCs) in pancreatic cancer and identified a novel DC-related gene signature that stratifies patient subtypes and implicates a KCTD14-TNF signaling axis. This study provides a
