Cancer research
A significant proportion of lung cancer patients may be malnourished, impacting outcomes in those undergoing resection. Researchers from Duke University have conducted a study to examine the effects of malnutrition on patient outcomes using modified Global Leadership Initiative on Malnutrition (GLIM) criteria. The study analyzed data from 37,386 patients
Cancer research
A new study on oncology-colorectal cancer has revealed that current decision-analytic models evaluating the effects of cancer screening may not accurately reflect the true benefits of screening. The research, published in Medical Decision Making, found that models predicting life expectancy gains from screening interventions varied in magnitude across different cancer
Cancer research
Researchers at UCLA and UC Davis will lead a $16 million clinical trial to determine whether artificial intelligence (AI) can improve mammogram accuracy and patient experience. The PRISM Trial will evaluate the impact of AI on mammogram accuracy, recall rates, and patient anxiety, with a focus on patient-centered research and
Cancer research
A clinical trial at the Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, aims to assess the effectiveness of artificial intelligence (AI) in supporting radiologists in interpreting mammograms. Led by Jose Net, M.D., the study will involve hundreds of thousands of mammograms and
Cancer research
Researchers at Monash University Malaysia have made a significant breakthrough in the treatment of brain cancer, using antibody-conjugated polymer nanoparticles to target and destroy cancer cells. According to the study, brain cancer remains a significant global health challenge, affecting over a million individuals worldwide, and the blood-brain barrier (BBB) has
Cancer research
The Lung Cancer Research Foundation (LCRF) and Oncology Advocates United for Climate and Health -- International (OUCH-I) are partnering to fund projects that examine the impact of environmental pollution and climate change on lung cancer risk, diagnosis, treatment, and outcomes. The program, titled OUCH-International and LCRF Research Grant Program on
Cancer research
A significant global health challenge, colorectal cancer (CRC) accounts for a substantial proportion of cancer cases and associated mortality. By 2040, new cases are projected to increase due to demographic factors such as aging and population growth. Despite advancements in understanding CRC pathophysiology, challenges persist, including drug resistance and adverse
Cancer research
A study examining brain metastases among patients with metastatic non-small cell lung cancer (mNSCLC) reveals disparities in diagnosis and treatment patterns, particularly in high poverty areas. Data from the Surveillance, Epidemiology, and End Results (SEER) program linked to Medicare claims were used to examine the prevalence of brain imaging at
Cancer research
A new study has been conducted to examine the concordance among 26 next-generation sequencing (NGS) laboratories participating in the National Cancer Institute's (NCI) Molecular Analysis for Therapy Choice (NCI-MATCH) clinical trial. The study aimed to compare variant detection and reporting between a wide range of testing platforms. Funded
Cancer research
Researchers at the Erasmus Medical Center have initiated a Phase 3 clinical trial to investigate the efficacy of adjuvant chemotherapy in preventing disease recurrence in patients with high-risk rectal cancer who have detectable circulating tumor DNA (ctDNA) after surgery. The trial, led by principal investigator Cornelis Verhoef, MD, PhD, aims
Cancer research
A recent study conducted by the Spanish Society of Medical Oncology (SEOM) has shed light on the risks associated with PARP inhibitors in ovarian cancer patients. The research aimed to determine the real-world incidence and predictive factors for venous and arterial thromboembolic events (VTE/AT) in patients treated with these
Cancer research
Researchers at Helwan University have made a significant breakthrough in understanding ovarian cancer, a leading cause of cancer deaths in women. A comprehensive study on gene expression and protein levels has identified KRAS and NOXA genes as promising biomarkers for ovarian cancer development and progression. The study, published in Scientific
