Cancer research
Researchers have discovered an association between oral bacteria and fungi and the development of pancreatic cancer. A study published in JAMA Oncology found that certain bacteria and fungi in the mouth are linked to an increased risk of pancreatic cancer. The study analyzed data from over 122,000 participants and
Cancer research
Researchers at the University of Manchester have conducted a study to evaluate the effectiveness of faecal immunochemical testing (FIT) in detecting colorectal cancer (CRC) in patients with cystic fibrosis (CF). The study found that FIT showed poor sensitivity and modest specificity in detecting polyps, and its utility as a screening
Cancer research
A recent study conducted by the Spanish Society of Medical Oncology (SEOM) has shed light on the risks associated with PARP inhibitors in ovarian cancer patients. The research aimed to determine the real-world incidence and predictive factors for venous and arterial thromboembolic events (VTE/AT) in patients treated with these
Cancer research
A new study on ovarian cancer has shed light on the critical role of microRNAs (miRNAs) in tumorigenesis and chemoresistance. The research identified specific miRNAs that are differentially expressed in clinical specimens of ovarian cancer patients, which may predict survival outcomes. The findings suggest that certain miRNAs, such as miR-182,
Cancer research
Recent research from the University of New Mexico has shed light on a novel therapeutic strategy for gynecologic cancers characterized by mutations in the tumor suppressor gene TP53. According to study results, ovarian and endometrial cancers frequently harbor TP53 mutations, resulting in unregulated cell growth and resistance to standard treatments.
Cancer research
A recent study published in Frontiers in Pharmacology explored the impact of ketamine on immune systems in patients undergoing laparoscopic colon cancer surgery. The research found that ketamine, an anesthetic with immune-protective effects, impairs anesthesia-induced immune suppression. However, more studies are needed to verify this finding and draw a solid
Cancer research
Haystack Oncology, a Quest Diagnostics company, has announced a research collaboration with the Rutgers Cancer Institute to evaluate the use of Haystack MRD, a highly sensitive ctDNA test, to help optimize postoperative therapy decisions in patients with stage II/III non-small cell lung cancer (NSCLC). The study, titled "Trial
Cancer research
Jonsson Comprehensive Cancer Center has listed an interventional clinical trial, Phase 2, to investigate the effectiveness of Eclipse: Flotufolastat F 18 in detecting residual or recurrent cancer after prostate focal therapy. The trial's principal investigator is Wayne Brisbane, and it is being conducted in collaboration with BLUE EARTH
Cancer research
Researchers from the University of California Los Angeles (UCLA) have conducted a study to determine the prevalence of pathogenic or likely pathogenic mutations in ovarian cancer. The study, published in the JCO Precision Oncology journal, analyzed 33,850 molecularly profiled ovarian cancer samples from real-world patients who underwent next-generation sequencing
Cancer research
Investigators at the University of Rochester published a new report on the use of estrogen therapy in patients with gynecologic cancer. The study aimed to evaluate the practice patterns of gynecologists and oncologists in the United States regarding the prescription of estrogen therapy to patients with a history of endometrial,
Cancer research
Researchers at Creighton University School of Medicine have published a study examining trends in lung cancer mortality rates in the United States from 1999 to 2022. The study, which utilized data from the Centers for Disease Control and Prevention's (CDC) Wide-ranging Online Data for Epidemiology Research (WONDER) database,
Cancer research
Researchers at NYU School of Medicine have discovered that certain oral bacteria and fungi can increase the risk of pancreatic cancer. The study, published in the JAMA Oncology journal, found that three specific oral bacteria - P gingivalis, E nodatum, and P micra - and one fungi, candida, are associated
