Cancer research
Current study results on cancer gene therapy have been published, revealing a potent immune stimulator that induces the proliferation and activation of natural killer (NK) and T cells and the secretion of interferon (IFN)-γ. Researchers at the University of South Florida have developed an advanced electrotransfer system that overcomes
Cancer research
Research conducted by Islamic Azad University, Zanjan, Iran, has led to a significant breakthrough in the development of a novel drug delivery system for oral cancer therapy. The study investigated the green synthesis of selenium nanoparticles (SeNPs) and their encapsulation in liposomes to enhance their antibacterial and anticancer properties. The
Cancer research
Research conducted by Washington University has made a significant breakthrough in the treatment of pancreatic cancer, a disease with a generally poor prognosis. By combining chemotherapy with a C-C chemokine receptor type 2 inhibitor, the study found that tumor-associated macrophages were targeted, leading to improved efficacy and restored T-cell immunity
Cancer research
A new report published by researchers at Nagoya City University Graduate School of Medical Sciences highlights the risk of cardiac dysfunction in patients with BRAF-mutated colorectal cancer receiving triple therapy consisting of encorafenib, binimetinib, and cetuximab. The study emphasizes the importance of early recognition and management of this adverse event
Cancer research
A new research study published in the Lancet Oncology journal has found that the combination of lenvatinib and pembrolizumab may be a potential standard treatment for patients with advanced B3 thymoma and thymic carcinoma. The study, conducted by researchers from Paris-Saclay University, involved 43 patients with relapsed or recurrent histologically
Cancer research
Research conducted at Thomas Jefferson University has demonstrated the efficacy of ASP-1929 photoimmunotherapy in combination with pembrolizumab in patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). The phase Ib/II study evaluated the safety and efficacy of the treatment, which involved administering ASP-1929 photoimmunotherapy in combination
Cancer research
Researchers from Sichuan University have made a significant breakthrough in the treatment of lung cancer, specifically squamous non-small cell lung cancer (sqNSCLC). A new study has demonstrated the efficacy of combining stereotactic body radiotherapy (SBRT), low-dose radiation (LDRT), sintilimab, and chemotherapy to improve outcomes for patients with locally advanced or
Cancer research
Researchers at Erasmus University Medical Center Cancer Institute have made a breakthrough in the treatment of gastric cancer, reporting promising results from a phase I trial of intraperitoneal irinotecan with systemic capecitabine and oxaliplatin. The trial, which involved patients with gastric cancer and peritoneal metastases, demonstrated a median overall survival
Cancer research
A new study published in the Journal of Cancer has identified a novel risk score model based on lactate-related genes that can predict radiotherapy outcomes in lung cancer. The study, conducted by researchers from the Department of Oncology at Haimen People's Hospital in Nantong, People's Republic
Cancer research
Researchers at Al-Nahrain University have published a new study on DNA-binding molecules, highlighting their crucial role in regulating gene expression, replication, repair, and transcription. The review investigated the architectures, processes, and impacts of these molecules on cancer research and therapy, aiming to determine their biological and therapeutic potential. The study
Cancer research
Nxera Pharma Co., Ltd. and Cancer Research UK have announced that the first patient has been dosed in a Phase 2a clinical trial evaluating the investigational immunotherapy drug HTL0039732 for advanced solid tumors. The trial, which is sponsored and managed by Cancer Research UK's Centre for Drug Development,
Cancer research
Research by scientists from the Icahn School of Medicine at Mount Sinai has shed light on the complex regulation of the O6-methylguanine-DNA methyltransferase (MGMT) enzyme, uncovering its role in DNA repair, cancer progression, and treatment resistance. According to the study, MGMT's regulatory balance is crucial in determining its
