Cancer research
New research in Oncology - Gastric Cancer reveals that lipid metabolism plays a critical role in the progression of gastric cancer, with complex metabolic reprogramming supporting tumor growth and survival. According to a peer-reviewed study published in the World Journal of Gastrointestinal Oncology, investigators have identified key enzymes and genes
Cancer research
Research by scientists from the Icahn School of Medicine at Mount Sinai has shed light on the complex regulation of the O6-methylguanine-DNA methyltransferase (MGMT) enzyme, uncovering its role in DNA repair, cancer progression, and treatment resistance. According to the study, MGMT's regulatory balance is crucial in determining its
Cancer research
Researchers at Al-Nahrain University have published a new study on DNA-binding molecules, highlighting their crucial role in regulating gene expression, replication, repair, and transcription. The review investigated the architectures, processes, and impacts of these molecules on cancer research and therapy, aiming to determine their biological and therapeutic potential. The study
Cancer research
Nxera Pharma Co., Ltd. and Cancer Research UK have announced that the first patient has been dosed in a Phase 2a clinical trial evaluating the investigational immunotherapy drug HTL0039732 for advanced solid tumors. The trial, which is sponsored and managed by Cancer Research UK's Centre for Drug Development,
Cancer research
A new study published in the Journal of Cancer has identified a novel risk score model based on lactate-related genes that can predict radiotherapy outcomes in lung cancer. The study, conducted by researchers from the Department of Oncology at Haimen People's Hospital in Nantong, People's Republic
Cancer research
Researchers from Fudan University have made a significant discovery in cancer gene therapy, shedding light on the potential relationship between lipid metabolic reprogramming and immunotherapy resistance in hepatocellular carcinoma (HCC). The study reveals that transforming acidic coiled-coil-containing protein 3 (TACC3) plays a crucial role in maintaining polyunsaturated fatty acid (PUFA)
Cancer research
Researchers at the Department of Radiology, Taikang Tongji (Wuhan) Hospital, have made significant contributions to the field of oncology by investigating the diagnostic accuracy of radiologists in assessing gastric and colorectal cancer patients with fluorouracil implants. The study, published in the journal Quantitative Imaging in Medicine and Surgery, aimed to
Cancer research
Recent research has shed new light on the effectiveness of high-dose biologically effective dose (BED) versus standard dose regimens in stereotactic body radiotherapy (SBRT) for localized prostate cancer. Investigators compared the safety and efficacy of high-dose BED versus standard dose regimens in a retrospective analysis of prostate-localized SBRT patients from
Cancer research
A recent study has shed new light on the potential benefits of cannabinoids in treating pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and lethal form of cancer, characterized by dismal survival rates. Cannabinoids, including tetrahydrocannabinol (THC) and cannabidiol (CBD), have shown promise in various cancer studies, but
Cancer research
Researchers at Heilongjiang University of Chinese Medicine have made a groundbreaking discovery in the field of cancer gene therapy, offering a new approach to combat colorectal cancer. According to a recent study, immunotherapy has been shown to be an effective treatment for colorectal cancer, but it is often hindered by
Cancer research
A recent study published in Cellular Signalling has revealed the underlying molecular mechanisms of sodium butyrate's anti-cancer properties against colorectal cancer (CRC). Research conducted by a team of scientists from Nanjing Medical University has demonstrated that sodium butyrate upregulates the long non-coding RNA LOH12CR2, which is crucial for
Cancer research
Researchers at Tianjin University have made a groundbreaking discovery in the field of cancer immunotherapy. Using a defined co-culture system of tumor-specific CTLs and cognate antigen-expressing tumor cells, the team observed that tryptophan (Trp) level is elevated in the tumor cell-activated CTLs. This finding led to the identification of a
