Cancer research
Research conducted at Fudan University has found that an anti-platelet factor 4 (PF4) antibody can inhibit the proliferation of lung cancer cells without TP53 mutation by inducing apoptosis and cell cycle arrest. The study, published in Clinical and Translational Discovery, used a co-culture system of platelets and lung cancer cells
Cancer research
A recent study published in Nucleosides, Nucleotides & Nucleic Acids has shed light on the role of HMGB1 in colon cancer. Researchers from Yancheng First People's Hospital in Jiangsu, China, investigated the association between a functional InDel polymorphism (rs34000982) on the HMGB1 gene and colon cancer susceptibility, tumor
Cancer research
Researchers from Liverpool and Macarthur Cancer Therapy Centres have published a study investigating the relationship between radiation dose to the bladder and urethra and genitourinary (GU) toxicity grade 2 in patients treated with stereotactic body radiation therapy (SBRT) for prostate cancer. The study found that delayed GU toxicity is experienced
Cancer research
Personalized medicine has undergone significant transformations in recent years, particularly in the treatment landscape of metastatic hormone-sensitive prostate cancer (mHSPC). According to a new report, researchers at the Rajiv Gandhi Cancer Institute and Research Centre (RGCIRC) have found that the treatment of mHSPC has undergone significant changes with the advent
Cancer research
National Cancer Institute (NCI) has announced an interventional clinical trial to assess the feasibility of a survivin peptide vaccine, called SurVaxM, as an interception agent in patients at high risk for lung cancer. The trial's principal investigator is Saikrishna S Yendamuri, and it aims to enroll 80 participants
Cancer research
Investigators at Sundsvall Hospital have been studying the effects of communication on cancer treatment outcomes. The research aimed to explore whether therapists' positive communication could strengthen positive treatment expectations and alleviate chemotherapy-induced nausea and vomiting. The study involved 198 patients with breast, colorectal, or bladder cancer undergoing neo-/adjuvant
Cancer research
Researchers at the National Institutes of Health (NIH) are studying a combination of immunotherapy drugs to help the immune system fight head and neck squamous cell carcinoma (HNSCC), a type of cancer with a low five-year survival rate of less than 50%. The trial, led by Charalampos Floudas, M.D.
Cancer research
Researchers at the University of Oxford's Nuffield Department of Primary Care Health Sciences have conducted a major UK study to analyze a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue. The study, published in the Lancet Primary Care, tracked
Cancer research
Research highlights the concerning prevalence of non-melanoma skin cancer in renal transplant recipients, particularly in those undergoing long-term immunosuppressive therapy. A recent study outlined the potential benefits of belatacept, a selective co-stimulation blocker, in reducing cancer risk while minimizing immunosuppression. However, the study also emphasized the need for further randomized
Cancer research
Researchers at I-Shou University in Taiwan have identified a potential therapeutic agent for treating gastric cancer. According to a new report, linolenic acid, a type of omega-3 fatty acid, has shown promising results in targeting cancer stemness and inducing apoptosis in gastric cancer cells. The study, published in Current Issues
Cancer research
A new study published in the Zhongguo Linchuang Yixue journal has highlighted the importance of personalized medicine in treating gastric cancer. The research, conducted by a team of scientists at Fudan University, utilizes gastric cancer organoids to predict a patient's sensitivity to chemotherapy drugs, thereby providing more effective
Cancer research
A recent study published in JAMA compared the use of biparametric (bpMRI) and multiparametric (mpMRI) MRI for prostate cancer diagnosis. The study, led by Prof Freddie Hamdy and Prof Jenny Donovan, found that bpMRI was non-inferior to mpMRI in detecting clinically significant disease. However, the authors emphasized several limitations of
