Cancer research
The report highlights the robust landscape of Colorectal Cancer (CRC) pipeline, with over 195 active players working to develop 200+ pipeline therapies. DelveInsight's 2025 report provides comprehensive insights into the CRC pipeline, including clinical trial studies, EMA, PDMA, FDA approvals, MOA, ROA, NDA, IND, and companies. Key Takeaways:
Cancer research
Researchers at Saveetha University have conducted a study to investigate the role of ABCE1 (ATP-binding cassette subfamily E member 1) as a potential biomarker for colorectal cancer (CRC). Through integrated bioinformatic analyses, the study highlights the significant oncogenic role of ABCE1 in CRC, opening new avenues for promising therapeutic interventions.
Cancer research
A team of researchers at Merck & Company in Rahway, New Jersey, has published a new study on cancer therapy, revealing key insights into the properties of vibostolimab, a humanized anti-T cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT) antibody. The study, titled "Pharmacological and structural characterization of vibostolimab,
Cancer research
Research findings on personalized medicine have shed new light on the early identification of high-risk recurrence patients in locally advanced rectal cancer. A study conducted by Koninklijke Philips N.V. - Philips Healthcare revealed that a 3D spectral CT-based fusion model can predict prognosis and postoperative adjuvant chemotherapy benefit in
Cancer research
Current study results reveal that cancer treatments have adverse effects on female fertility, leading to a growing number of girls and women facing reproductive health challenges. Researchers from the University of Colorado have found that radiation and chemotherapy can cause permanent damage to the ovaries and uterus, resulting in a
Cancer research
Researchers at Huashan Hospital Affiliated to Fudan University have initiated a clinical trial to investigate the occurrence and associated factors of postoperative upper limb dysfunction in breast cancer patients, with the aim of providing a scientific basis for developing personalized intervention strategies. The study will utilize wearable devices monitoring shoulder
Cancer research
A recent study published in the BMC Cancer journal has highlighted the complexities in standardizing stereotactic ablative radiation therapy (SABR) for recurrent ovarian cancer. The research, funded by the Ministry of Health and Welfare, aimed to assess treatment planning consistency and protocol adherence in a prospective, randomized, multicenter phase III
Cancer research
Researchers at the First Affiliated Hospital of Anhui Medical University in China have discovered that circulating extrachromosomal circular DNA (eccDNA) in the plasma can be used as a biomarker to predict chemotherapy sensitivity in epithelial ovarian cancer (EOC) patients. The study, published in Experimental Cell Research, found that EOC patients
Cancer research
According to a recent study published in the Journal of the American Nutrition Association, researchers at Wroclaw Medical University in Poland have found that phytoestrogens, found in foods such as soy products and flaxseed, may help reduce the risk of breast cancer in postmenopausal women. The study, titled "Comprehensive
Cancer research
Research on non-small cell lung cancer (NSCLC) has shown that microwave ablation (MWA) is an effective treatment option for elderly patients with stage I NSCLC. According to a recent study published in Cancer Imaging, the efficacy of MWA for patients aged 75 years with stage I NSCLC was evaluated, and
Cancer research
Akeso, Inc. has announced the enrollment and dosing of the first patient in the pivotal Phase III clinical trial evaluating cadonilimab, a first-in-class PD-1/CTLA-4 bispecific antibody, in combination with chemotherapy for the perioperative treatment of resectable gastric/gastroesophageal junction adenocarcinoma. This trial represents the third Phase III study for
Cancer research
A breakthrough in gastric cancer treatment has been reported by researchers at Nanjing Medical University in Jiangsu, People's Republic of China. A 35-year-old female patient with recurrent and metastatic gastric cancer, who had previously failed multiple therapies, including chemotherapy and immunotherapy, achieved complete remission after undergoing a novel
