Cancer research - Strategic Insights Report (Page 51)

Cancer research

Elpis Biopharmaceuticals Partners with National Cancer Centre Singapore to Develop Bispecific Armored CAR-T Therapies

Elpis Biopharmaceuticals, a clinical-stage cell therapy company, has announced a partnership with the National Cancer Centre Singapore (NCCS) to support collaborative cell therapy research and clinical trials for the treatment of various cancers, including colorectal, pancreatic, and ovarian cancers. The partnership aims to accelerate the development of next-generation cell therapies

Cancer research

Lurbinectedin as a Second-line Treatment for High-grade Pancreatic Neuroendocrine Tumors Under Clinical Trial

Researchers at the National Cancer Center, Korea, are conducting a Phase 2 clinical trial to study the efficacy of lurbinectedin as a second-line treatment for high-grade pancreatic neuroendocrine tumors (pNETs). The trial aims to enroll 46 participants from the USA and is currently active but not open for recruiting. The

Cancer research

Dissolving Microneedles Show Promise in Cancer Gene Therapy

Researchers at the University of Washington have conducted a comprehensive review of dissolving microneedles for nucleic acid delivery, highlighting their potential in cancer gene therapy. The study, published in Acta Biomaterialia, analyzed existing preclinical data to identify correlations between microneedle form and function, revealing that 83% of studies showed equivalent

Cancer research

Safety Profile of Nivolumab-Relatlimab in Cancer Patients: A Living Pharmacovigilance Study

A new study on the safety profile of nivolumab-relatlimab in cancer patients has been published in the European Journal of Pharmacology. The research integrated data from clinical trials and the FDA Adverse Event Reporting System (FAERS) database to assess the safety profile of the treatment. The study found that the

Cancer research

COVID-19 Outcomes in Cancer Patients: National Cancer Institute Study Reveals Key Risk Factors and Insights

A newly published study from the National Cancer Institute (NCI) has shed light on the critical factors influencing COVID-19 outcomes in cancer patients. The research, which was conducted as part of the National Cancer Institute COVID-19 in Cancer Patients Study (NCCAPS), aimed to identify risk factors for hospitalization and death

Cancer research

Reversing the "Cold" Tumor Microenvironment in Prostate Cancer

A recent study published in the Journal of Translational Medicine has shed light on the potential mechanisms for reversing the "cold" tumor microenvironment in prostate cancer. Researchers from Beijing Hospital, led by Rui Guo, identified 252 nonsynonymous somatic mutations in the RM-1 murine prostate cancer model, of which

Cancer research

Co-targeting TGF-β and PD-L1 Enhances Chemotherapy in Triple-Negative Breast Cancer

In a groundbreaking study conducted at the University of Bourgogne in Dijon, France, researchers have uncovered a novel approach to treating triple-negative breast cancer (TNBC), one of the most aggressive and deadly forms of the disease. The study reveals that co-targeting TGF-β (transforming growth factor-beta) and PD-L1 (programmed death-ligand 1)

Cancer research

Elevated Keratin 8 Expression Linked to Increased Immune-Related Pneumonitis Risk in Lung Adenocarcinoma Patients

Research conducted at the Third Hospital of Shanxi Medical University has revealed a significant correlation between elevated keratin 8 (KRT8) expression and the risk of developing immune-related pneumonitis (IRP) in lung adenocarcinoma patients undergoing immunotherapy. The study, which involved 36 patients, found that each percentage increase in KRT8 expression was

Cancer research

Breakthrough in Breast Cancer Treatment: New Nanoparticle Formulation Shows Promising Results

Scientists at the Institute of Medicinal Plant Development have developed a novel nanoparticle-based approach to enhance chemoimmunotherapy against 4T1 breast cancer. The research, funded by the Chinese Academy of Medical Sciences Initiative For Innovative Medicine, presents a significant advancement in cancer therapy. The new formulation, which combines squamocin with MnO2

Cancer research

New Insights into Interstitial Lung Disease Treatment

New research conducted by a team of experts at the Shinshu University School of Medicine has shed light on the treatment of Interstitial Lung Disease (ILD), a condition that can be caused by lung cancer. The study, published in the Respiratory Investigation journal, analyzed data from 181 patients with extensive-disease

Cancer research

Improved Survival Rates for Prostate Cancer Patients with PSMA PET/CT

A new study from Denmark reveals that men with biochemically recurrent prostate cancer who undergo PSMA PET/CT before salvage radiotherapy have significantly improved survival rates compared to those who do not. The study, published in the August issue of The Journal of Nuclear Medicine, used data collected nationwide over

Cancer research

Unlocking the Role of OCT4 in Cancer Lineage Plasticity

Researchers at the University of Kentucky have made new discoveries in cancer gene therapy, specifically focusing on the role of OCT4 in mediating lineage plasticity in prostate cancer. The study, published in the journal Biomedicines, highlights the importance of understanding the molecular mechanisms underlying OCT4-driven plasticity to develop novel therapeutic

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