Cancer research
Researchers from the University of Queensland have made significant breakthroughs in generating induced pluripotent stem cell (iPSC)-derived natural killer (NK) cells for cancer immunotherapy. According to a recent review published in Clinical & Translational Immunology, these cells hold promise as a scalable, consistent, and inexhaustible source of genetically modifiable
Cancer research
Cancer diagnosis brings about not only significant emotional toll but also substantial financial burdens for patients. A recent study published in JAMA Network Open sheds light on this critical issue, highlighting the staggering increase in out-of-pocket costs for individuals after receiving a cancer diagnosis. By analyzing a sample of over
Cancer research
The UK Parliament emphasizes the significance of research in tackling cancer, investing £1.6 billion per year through the National Institute for Health and Care Research (NIHR). Cancer research is a top priority, with £133 million allocated in 2023-2024. The TRANSFORM trial is a notable example of this investment, aiming
Cancer research
Yunnan Cancer Hospital has registered a clinical trial to investigate the efficacy of metformin hydrochloride extended release tablets in combination with immune checkpoint inhibitors to treat advanced or metastatic lung squamous cell carcinoma. The study aims to enroll 70 participants with locally advanced or metastatic squamous non-small cell lung cancer
Cancer research
Research conducted at Johns Hopkins University has shed light on the effects of immunotherapy on bone marrow interactions in patients with acute myeloid leukemia (AML). The study employed a multiomic approach, combining single-cell RNA sequencing with single-cell spatial transcriptomics, to analyze the interactions between leukemia cells and immune cells post-immunotherapy
Cancer research
A recent surge in early-stage colorectal cancer diagnoses among adults under 50 has been linked to increased screening, but experts say more work is needed to understand the underlying causes of the trend. In 2018, the American Cancer Society updated its guidelines to recommend screening starting at age 45, and
Cancer research
Medical researchers in China are exploring a new treatment approach for locally advanced rectal cancer by combining neoadjuvant therapy with citrus flavonoid tablets. The clinical trial, registered with the Chinese Clinical Trial Registry, aims to evaluate the efficacy and safety of this combination regimen in patients with high YWHAB expression.
Cancer
Research from the University of New South Wales's Drug Policy Modelling Program suggests that cancer warning labels on alcohol are crucial to inform consumers of the substance's link to several types of cancer. The World Health Organization (WHO) has classified alcohol as a Group 1 carcinogen,
Cancer research
Researchers at Stanford University have made a groundbreaking discovery in the diagnosis of pancreatic cancer, a disease that has a poor prognosis due to late-stage detection. According to a recent study published in Heliyon, the team of scientists leveraged machine learning techniques to identify a biologically relevant gene signature that
Cancer research
Researchers in Singapore have made significant advancements in the diagnosis of metastatic non-small cell lung cancer using a new liquid biopsy technology. The study, conducted by a team from Tan Tock Seng Hospital, evaluated the performance of a circulating tumor DNA (ctDNA) and circulating tumor RNA (ctRNA) liquid biopsy, LiquidHALLMARK
Cancer research
A pioneering study led by the Break Through Cancer team has shed new light on the recalcitrant nature of ovarian cancer, which often recurs despite initial treatment. Using minimally invasive surgery and blood tests, researchers discovered that nearly half of patients who appeared cancer-free on scans still harbored hidden cancer
Cancer research
Cancer researchers at Pontifical University Javeriana and Stanford University have discovered that informatics solutions can facilitate clinical trial screening, improving patient engagement and enrollment. They designed and implemented a personalized clinical trial matching system that integrated electronic medical records, clinical trials management systems, and a third-party software-based solution to directly
