Cancer research
A new research study has shed light on the effectiveness of avelumab first-line maintenance in patients with advanced urothelial carcinoma (UC). The study, led by researchers at the University of Washington, has provided insights into the real-world outcomes of this treatment approach, which has been approved for patients who are
Cancer research
Researchers at the University of Lodz in Poland have published a comprehensive review of the therapeutic potential of emerging PD-1/PD-L1-targeted antibodies in colorectal cancer. The study highlights the current treatment options, including pembrolizumab, nivolumab, and dostarlimab, and explores the challenges and complexities of combination strategies. The researchers aim to
Cancer research
Researchers from the Dana-Farber Cancer Institute have made significant strides in cancer immunotherapy, presenting a novel biomaterial-based vaccine that shows potential in treating metastatic melanoma. The innovative vaccine, known as WDVAX, has been tested in a phase I clinical trial and has demonstrated the ability to induce immune activation in
Cancer research
According to a new study, patients often fail to follow through with a colonoscopy after receiving an abnormal result on a blood-based test for colon cancer. Despite its non-invasive nature, the test only works if individuals complete the recommended follow-up procedure. Researchers examined Medicare claims data for over 6,000
Cancer research
Researchers have published new findings on the use of perioperative chemoimmunotherapy in patients with resectable stage II to IIIA non-small cell lung cancer (NSCLC). The study, which analyzed data from over 1,300 patients, found that those who received chemoimmunotherapy had improved clinical distant metastasis-free survival rates compared to those
Cancer research
Researchers at the University of Colorado Anschutz Medical Campus, Montefiore Einstein Comprehensive Cancer Center, and Utrecht University have found that common respiratory infections, including COVID-19 and influenza, can awaken dormant breast cancer cells in the lungs. This discovery was made by analyzing mouse models and two population studies, which showed
Cancer research
Researchers from the Faculty of Pharmaceutical Sciences have conducted a study on the direct costs and cost drivers of perioperative and adjuvant systemic treatments for stage I-II non-small cell lung cancer (NSCLC) in Jordan. The study used micro-costing methodology to analyze direct medical expenses, including drug acquisition, preparation, administration, pre/
Cancer research
Researchers at the University of Colorado Anschutz Medical Campus, Montefiore Einstein Comprehensive Cancer Center, and Utrecht University have found that common respiratory infections, including COVID-19 and influenza, can awaken dormant breast cancer cells in the lungs. This discovery was made by analyzing mouse models and two population studies, which showed
Cancer research
Researchers have developed a tumor growth inhibition- overall survival (TGI-OS) model for hormone receptor-positive (HR+)/human epidermal growth factor receptor 2 negative (HER2-) breast cancer using clinical trial data available through Vivli, a clinical trial data sharing platform. The TGI-OS model, a parametric model linking TGI metrics and baseline predictors
Cancer research
Researchers from Quaid-I-Azam University have made significant progress in understanding breast cancer, identifying key biomarkers, and developing novel therapeutic agents. The study, published in the Journal of Chemical Information and Modeling, employed network-based gene expression profiling to identify differentially expressed genes (DEGs) as potential biomarkers in breast cancer. The analysis
Cancer research
Research conducted in a large integrated healthcare system in the United States has found no conclusive evidence of an association between oral antibiotic use in adulthood and risk of early-onset colorectal cancer (EOCRC). The study aimed to evaluate the link between prior antibiotic use and EOCRC, as the incidence of
Cancer research
Despite the notion that a cancer diagnosis provides a "teachable moment" for adopting a healthier lifestyle, a recent study found that cancer survivors do not exhibit improved dietary awareness or healthier eating behaviors compared to individuals without cancer. Researchers analyzed data from the Health Information National Trends Survey,
