Cancer research
Advanced-stage prostate cancer, known as metastatic hormone refractory prostate cancer (mHRPC), poses significant treatment challenges. The disease progresses despite anti-androgen treatments, resulting in cancer spreading to bones and lymph nodes. Symptoms include persistent bone pain, fatigue, weight loss, and urinary issues, which can significantly decrease patient quality of life. The
Cancer research
Researchers at Majmaah University have made a significant breakthrough in breast cancer screening using artificial intelligence-powered infrared thermography. The new system, which utilizes convolutional neural networks (CNNs) and enhanced particle swarm optimization algorithm, has achieved a superior classification accuracy of 98.8%. This marks a significant improvement over conventional CNN
Cancer research
Women are more likely to take up the offer of a DIY cervical cancer test if they are offered it by a GP during a routine appointment, a study suggests. Researchers from Queen Mary University of London and King's College London found that women who were "opportunistically&
Cancer research
Women born before 1990 can reduce their risk of cervical cancer by 80 to 90 per cent if they undergo regular screening. The current cervical screening rate in the UK is at its lowest point in almost 20 years, with only 66 per cent of eligible women up to date
Cancer research
Jiangsu Cancer Hospital has initiated a clinical trial to study the efficacy and safety of Apatolimab Tovolimab combined with regorafenib and paclitaxel as a second-line treatment for patients with advanced gastric or gastroesophageal junction (G/GEJ) adenocarcinoma who have failed immunotherapy combined with chemotherapy. The open-label, multicenter phase II clinical
Cancer research
A new breast cancer screening study, FAST MRI DYAMOND, is exploring whether a faster magnetic resonance imaging (MRI) scan can detect 'hard to spot' cancers earlier in women with average breast density. Led by North Bristol NHS Trust, the study aims to detect cancers that may not be
Cancer research
North Bristol NHS Trust's FAST MRI DYAMOND study is investigating whether a new, faster magnetic resonance imaging (MRI) scan, FAST MRI, can detect breast cancers earlier for women in their early fifties. The study is focusing on women with average breast density and aims to detect cancers that
Cancer research
Mayo Clinic is leading an interventional clinical trial, Phase 2, to investigate the potential benefits of combining therapeutic plasma exchange (TPE) with existing treatments for bladder cancer. The trial aims to recruit 50 participants from the USA and is designed to compare the effectiveness of TPE, followed by enfortumab vedotin
Cancer research
Researchers at the University of Michigan and Oregon Health & Science University have identified a gene program associated with extreme non-response to a common prostate cancer drug, enzalutamide. The study, led by Joshi Alumkal and Zheng Xia, sheds light on why some tumors are treatment-resistant and explores potential new treatment
Cancer research
The kidney cancer research community is crying out for continued support from congressional funding to ensure that patients with renal cell carcinoma (RCC) and other disease types receive cutting-edge treatments. Eric Jonasch, MD, emphasizes the importance of extending funding for the benefit of patients with RCC. The Kidney Cancer Research
Cancer research
Investigators at the National Cancer Center in South Korea have published a new study on the clinical significance of circulating tumor DNA (ctDNA) KRAS mutations in patients with pancreatic adenocarcinoma (PAC). The research aimed to propose a cut-off value of mutant KRAS (mKRAS) concentration in ctDNA and validate its clinical
Cancer research
Researchers at Chongqing Medical University in Chongqing, People's Republic of China, have made a significant discovery in the field of cancer research, unveiling the crucial role of urea transporters (UTs) in human diseases. The study, published in Sub-cellular Biochemistry, reveals that UT-B and UT-A, encoded by Slc14A1 and
