Cancer research
Researchers at a leading institution are conducting a Phase 2 clinical trial to investigate metabolic glycolytic biomarkers predictive of response to neoadjuvant immunotherapy in non-small cell lung cancer (NSCLC). The trial, led by Saulo B. Silva, Associate Professor, MD, PhD, aims to develop a practical diagnostic approach to improve patient
Cancer research
The Roswell Park Cancer Institute has announced the launch of an interventional clinical trial to study the effectiveness of GB1211 (selvigaltin), an oral galectin-3 inhibitor, in combination with standard of care treatment in patients with relapsed or refractory multiple myeloma. The trial, which has an enrollment of 21 participants from
Cancer research
Hunan Cancer Hospital has launched a Phase 2 clinical trial to evaluate the efficacy and safety of lorlatinib in treating advanced ROS1-positive non-small cell lung cancer (NSCLC) patients with brain metastases. The trial aims to enroll 21 participants from the USA and will assess the intracranial efficacy and safety of
Cancer research
Chris O'Brien Lifehouse has launched the ACTIDIET-PRO study, a clinical trial to assess the effects of a lifestyle intervention on physical activity and diet in patients with metastatic prostate cancer receiving novel hormonal agents. The study aims to evaluate the feasibility of an exercise and diet intervention in
Cancer research
A groundbreaking study led by Dr. Stephen D. Nimer, Director of Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has revealed a key regulator of gene expression called TAF1 as a potential drug target in leukemia and other blood cancers. The study, published in the
Cancer research
Colorectal cancer remains a significant health issue in the United States, with Black communities disproportionately affected due to a range of social determinants and access issues. Despite being one of the most preventable and treatable cancers, the incidence and mortality rates for Black individuals are about 20% and 30% higher
Cancer research
Scientists at Northwestern University have made a significant discovery in the field of cancer therapy, specifically in the treatment of brain tumors. Their research reveals that immunotherapy, a revolutionary approach in cancer treatment, can effectively combat brain tumors by harnessing the power of B-cell immunity. According to the study, B
Cancer research
Research presented from Jiangsu, People's Republic of China, has demonstrated significant advancements in bladder cancer immunotherapy, particularly in addressing limitations of the current gold standard, Bacillus Calmette-Guerin (BCG). Investigators at Kunshan Hospital of Traditional Chinese Medicine have shown that novel combinations of sasanlimab (a PD-1 monoclonal antibody) with
Cancer research
New research conducted in the People's Republic of China suggests that internet-based nursing guidance may have a significant impact on reducing the risk of postoperative upper limb lymphedema in breast cancer patients. The study, which included 208 female patients who underwent breast and lymph node surgery between 2020
Cancer research
Researchers from Northwestern University have presented fresh data on the use of artificial intelligence (AI) algorithms to analyze radiomic features in non-small cell lung cancer (NSCLC) patients undergoing immunotherapy. The study analyzed data from 159 stage III-IV NSCLC patients and found that radiomics models could predict the occurrence of checkpoint
Cancer research
Research at the Dr. Josep Trueta University Hospital in Catalonia, Spain, has uncovered a promising combination therapy for non-small cell lung cancer (NSCLC) patients with brain metastases (BM). The study, published in Frontiers in Medicine, demonstrates that silibinin, a flavonolignan with known blood-brain barrier permeability and anti-BM activity, can enhance
Cancer research
Researchers at Emory University have uncovered unique genetic and pathologic differences in endometrial cancer between Black and white women. The study, published in NPJ Precision Oncology, found that Black women with endometrial cancer have a higher proportion of subtypes with higher mortality rates, despite having lower survival rates. The team
