Cancer research
A recent study by Hungkuang University's Hsu Yu-huan has shed light on the critical role of psychological triggers in motivating individuals to undergo cancer screening in Taiwan. The study, which analyzed 600 valid survey responses, identified three key determinants of screening behavior: cues to action, self-efficacy, and perceived
Cancer research
Research published in ESMO Open has demonstrated the long-term effectiveness of nivolumab plus ipilimumab with chemotherapy as a first-line treatment option for patients with metastatic non-small-cell lung cancer (NSCLC). The phase III CheckMate 9LA study, led by Ohio State University, showed that this regimen provided a sustained overall survival (OS)
Cancer research
A new study published in Transplant Immunology has found that the immune checkpoint inhibitor Cemiplimab can be safely used in high immunologic risk kidney transplant recipients with metastatic squamous cell carcinoma. The study, led by researchers at the Cleveland Clinic, reported a case of a patient who received Cemiplimab as
Cancer research
New research from Memorial Sloan-Kettering Cancer Center has made significant findings on genetic evolution in cancer during metastasis, providing new insights into the progression of the disease. According to the study, tumors accumulate copy number alterations (CNAs) to a much greater degree than mutations during distant metastasis. The researchers analyzed
Cancer research
Current research suggests that CD40 agonists, a type of immunotherapeutic agent, may be a promising approach to treating cancer. By licensing dendritic cells to prime tumor-specific T cells, polarizing macrophages to a proinflammatory phenotype, and activating B cells, CD40 agonists have shown significant potential in inducing antitumor immunity. However, clinical
Cancer research
Researchers at Nagoya University have discovered a potential new therapeutic target for head and neck squamous cell carcinoma (HNSCC) by investigating the function of the long non-coding RNA Taurine upregulated 1 (TUG1). The study, which was published in the Nagoya Journal of Medical Science, found that TUG1 is overexpressed in
Cancer research
In a groundbreaking mission, scientists from the University of California San Diego (UCSD) are conducting research on a potential new cancer treatment in space, aboard the International Space Station. The study, funded by NASA, aims to analyze the effects of the drug rebecsinib on various types of cancer, including ovarian
Cancer research
Researchers from National Hospital Organization have developed and validated a machine-learning model to predict postoperative functional disability and mortality in older patients with cancer. According to the study, the global cancer burden is rapidly increasing, with an estimated 20 million new cases in 2022. The population aged 65 years is
Cancer research
Research has highlighted the gap in the validation of wearable devices in populations with cancer, particularly in patients with lung cancer, who experience unique mobility challenges and gait impairments. A recent study aims to address this gap by validating the Fitbit Charge 6, ActiGraph LEAP, and activPAL3 micro in patients
Cancer research
Researchers at AlMaarefa University have discussed new findings in personalized medicine, specifically focusing on the application of artificial intelligence (AI) in the detection and management of lung cancer. The study introduces an innovative method called CTGAN-RF, which uses conditional tabular generative adversarial networks (CTGAN) and random forest (RF) classifier to
Cancer research
A recent study by researchers at the Kaiser Permanente Division of Research has found that a blood-based test for colorectal cancer detection shows promising results, with a sensitivity of 79.2% and specificity of 91.5% in an average-risk population. The study, which involved 27,010 participants, demonstrated the potential
Cancer research
Researchers at the University of Texas Houston have conducted a study on the cutaneous adverse effects (CAEs) associated with the combination of epidermal growth factor receptor inhibitors (EGFRIs) and immune checkpoint inhibitors (ICIs) in cancer therapy. The study found that 59% of patients treated with this combination therapy developed a
